[HTML][HTML] Liposomes: structure, biomedical applications, and stability parameters with emphasis on cholesterol
P Nakhaei, R Margiana, DO Bokov… - … in bioengineering and …, 2021 - ncbi.nlm.nih.gov
Liposomes are essentially a subtype of nanoparticles comprising a hydrophobic tail and a
hydrophilic head constituting a phospholipid membrane. The spherical or multilayered …
hydrophilic head constituting a phospholipid membrane. The spherical or multilayered …
The blood–tumour barrier in cancer biology and therapy
PS Steeg - Nature Reviews Clinical Oncology, 2021 - nature.com
The protective blood–brain barrier has a major role in ensuring normal brain function by
severely limiting and tightly controlling the ingress of substances into the brain from the …
severely limiting and tightly controlling the ingress of substances into the brain from the …
Progress in nasal drug delivery systems
F Laffleur, B Bauer - International Journal of Pharmaceutics, 2021 - Elsevier
Most of the available drugs are usually administered orally (eg in tablets or capsules) or by
parenteral injection in the case of substances being destroyed in the gastric environment or …
parenteral injection in the case of substances being destroyed in the gastric environment or …
[HTML][HTML] Recent advances in intranasal liposomes for drug, gene, and vaccine delivery
Liposomes are safe, biocompatible, and biodegradable spherical nanosized vesicles
produced from cholesterol and phospholipids. Recently, liposomes have been widely …
produced from cholesterol and phospholipids. Recently, liposomes have been widely …
Improving drug delivery for Alzheimer's disease through nose-to-brain delivery using nanoemulsions, Nanostructured Lipid Carriers (NLC) and in situ hydrogels
Current treatments for Alzheimer's disease (AD) attenuate the progression of symptoms and
aim to improve the patient's quality of life. Licensed medicines are mostly for oral …
aim to improve the patient's quality of life. Licensed medicines are mostly for oral …
[HTML][HTML] Pharmacokinetics and pharmacodynamics of intranasal solid lipid nanoparticles and nanostructured lipid carriers for nose-to-brain delivery
TTL Nguyen, HJ Maeng - Pharmaceutics, 2022 - mdpi.com
Nose-to-brain drug delivery has been of great interest for the treatment of many central
nervous system (CNS) diseases and psychiatric disorders over past decades. Several …
nervous system (CNS) diseases and psychiatric disorders over past decades. Several …
Exploring the impact of physicochemical properties of liposomal formulations on their in vivo fate
Liposomes, vesicles composed of a phospholipid bilayer, are considered a remarkably
advanced drug delivery system due to their unique properties, including their …
advanced drug delivery system due to their unique properties, including their …
Recent progress in nanocarriers for direct nose to brain drug delivery
Nose to brain drug delivery is considered as a viable option to deliver various therapeutic
agents with low cerebral bioavailability bypass blood-brain barrier (BBB). The drug …
agents with low cerebral bioavailability bypass blood-brain barrier (BBB). The drug …
[HTML][HTML] Using the intranasal route to administer drugs to treat neurological and psychiatric illnesses: rationale, successes, and future needs
While the intranasal administration of drugs to the brain has been gaining both research
attention and regulatory success over the past several years, key fundamental and …
attention and regulatory success over the past several years, key fundamental and …
[HTML][HTML] Nanoparticle-guided brain drug delivery: Expanding the therapeutic approach to neurodegenerative diseases
C Riccardi, F Napolitano, D Montesarchio, S Sampaolo… - Pharmaceutics, 2021 - mdpi.com
Neurodegenerative diseases (NDs) represent a heterogeneous group of aging-related
disorders featured by progressive impairment of motor and/or cognitive functions, often …
disorders featured by progressive impairment of motor and/or cognitive functions, often …