The incidence of inflammatory bowel disease (IBD) is rapidly rising throughout the world.
Although tremendous efforts have been made, limited therapeutics are available for IBD …

Colitis-associated colorectal cancer is the most serious complication of ulcerative colitis.
Long-term chronic inflammation increases the incidence of CAC in UC patients. Compared …

Orally targeted strategy of anti-inflammatory agents has attracted tremendous attention for
reducing highly health-care costs and enhancing the intervention efficiency of ulcerative …

Restoring immune balance by targeting macrophage polarization is a potentially valuable
therapeutic strategy for ulcerative colitis (UC). Dioscin is a steroidal saponin with potent anti …

Although magnolol (Mag), an anti-inflammatory natural compound, has been demonstrated
to play protective effects on ulcerative colitis (UC), its application as an alternative …

Although nano-systems can promote the cellular internalization, polymeric nanoparticles
(NPs) are easily to be destroyed or eliminated in the gastrointestinal tract, which leads to …

Colonic epithelial damage and dysregulated immune response are crucial factors in the
progression and exacerbation of inflammatory bowel disease (IBD). Nanoenabled targeted …

Macrophages play a crucial role in the pathogenesis of pancreatitis that is a common
gastrointestinal disease. Particularly, macrophages differentiate into different phenotypes …

Co-delivery of anti-inflammatory drugs and reactive oxygen species (ROS) scavengers by
stimuli-responsive oral nanoparticles is deemed to be a favorable strategy for inflammatory …

Ulcerative colitis (UC) faces some barriers in oral therapy, such as how to safely deliver
drugs to the colon and accumulate in the colon lesions. Hence, we report an advanced yeast …