The intestinal barrier is a precisely regulated semi-permeable physiological structure that
absorbs nutrients and protects the internal environment from infiltration of pathological …

The gut microbiota plays a key role in host health and disease, particularly through their
interactions with the immune system. Intestinal homeostasis is dependent on the symbiotic …

Ulcerative colitis (UC) is a common inflammatory bowel disease driven by the
dyshomeostasis of intestinal immune system and microbiota, but its treatment options are …

According to reports, gut microbiota and metabolites regulate the intestinal immune
microenvironment. In recent years, an increasing number of studies reported that bile acids …

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disorder worldwide.
Recent studies show that innate immunity-related signaling pathways fuel NAFLD …

The brain and gut are intricately connected and respond to various stimuli. Stress-induced
brain-gut communication is implicated in the pathogenesis and relapse of gut disorders. The …

Bile acids, such as taurochenodeoxycholic acid (TCDCA), are considered as functional
small molecules involved in nutrition regulation or acting with adjuvant therapeutic effects …

Global warming is one of the most common environmental challenges faced by cold-water
fish farming. Intestinal barrier function, gut microbiota, and gut microbial metabolites are …

The gut mucosal epithelium is one of the largest organs in the body and plays a critical role
in regulating the crosstalk between the resident microbiome and the host. To this effect, the …

Abstract 12α-Hydroxylated (12αOH) bile acids (BAs) selectively increase with high-fat diet
intake. Dietary supplementation with cholic acid (CA) in rats is a possible strategy to reveal …