[HTML][HTML] High monoclonal neutralization titers reduced breakthrough HIV-1 viral loads in the Antibody Mediated Prevention trials
Abstract The Antibody Mediated Prevention (AMP) trials (NCT02716675 and
NCT02568215) demonstrated that passive administration of the broadly neutralizing …
NCT02568215) demonstrated that passive administration of the broadly neutralizing …
[HTML][HTML] Prospects for passive immunity to prevent HIV infection
L Morris, NN Mkhize - PLoS Medicine, 2017 - journals.plos.org
Prospects for passive immunity to prevent HIV infection | PLOS Medicine Skip to main content
Advertisement PLOS Medicine Browse Current Issue Journal Archive Special Issues Collections …
Advertisement PLOS Medicine Browse Current Issue Journal Archive Special Issues Collections …
[HTML][HTML] Distinct, IgG1-driven antibody response landscapes demarcate individuals with broadly HIV-1 neutralizing activity
Understanding pathways that promote HIV-1 broadly neutralizing antibody (bnAb) induction
is crucial to advance bnAb-based vaccines. We recently demarcated host, viral, and disease …
is crucial to advance bnAb-based vaccines. We recently demarcated host, viral, and disease …
Prime-boost immunizations with DNA, modified vaccinia virus Ankara, and protein-based vaccines elicit robust HIV-1 tier 2 neutralizing antibodies against the CAP256 …
MT van Diepen, R Chapman, N Douglass… - Journal of …, 2019 - Am Soc Microbiol
ABSTRACT A vaccine regimen that elicits broadly neutralizing antibodies (bNAbs) is a major
goal in HIV-1 vaccine research. In this study, we assessed the immunogenicity of the …
goal in HIV-1 vaccine research. In this study, we assessed the immunogenicity of the …
Passive and active antibody studies in primates to inform HIV vaccines
AJ Hessell, DC Malherbe… - Expert review of vaccines, 2018 - Taylor & Francis
Introduction: Prevention of infection remains the ultimate goal for HIV vaccination, and there
is compelling evidence that antibodies directed to Envelope are necessary to block infection …
is compelling evidence that antibodies directed to Envelope are necessary to block infection …
[HTML][HTML] Mathematical modeling to reveal breakthrough mechanisms in the HIV Antibody Mediated Prevention (AMP) trials
The ongoing Antibody Mediated Prevention (AMP) trials will uncover whether passive
infusion of the broadly neutralizing antibody (bNAb) VRC01 can protect against HIV …
infusion of the broadly neutralizing antibody (bNAb) VRC01 can protect against HIV …
Coevolution of HIV-1 and broadly neutralizing antibodies
NA Doria-Rose, E Landais - Current Opinion in HIV and AIDS, 2019 - journals.lww.com
Coevolution of HIV-1 and broadly neutralizing antibodies : Current Opinion in HIV and AIDS
Coevolution of HIV-1 and broadly neutralizing antibodies : Current Opinion in HIV and AIDS Log …
Coevolution of HIV-1 and broadly neutralizing antibodies : Current Opinion in HIV and AIDS Log …
Predicting in vivo escape dynamics of HIV-1 from a broadly neutralizing antibody
M Meijers, K Vanshylla, H Gruell… - Proceedings of the …, 2021 - National Acad Sciences
Broadly neutralizing antibodies are promising candidates for treatment and prevention of
HIV-1 infections. Such antibodies can temporarily suppress viral load in infected individuals; …
HIV-1 infections. Such antibodies can temporarily suppress viral load in infected individuals; …
Broadly neutralizing antibodies for HIV prevention: a comprehensive review and future perspectives
S Mahomed - Clinical Microbiology Reviews, 2024 - Am Soc Microbiol
The human immunodeficiency virus (HIV) epidemic remains a formidable global health
concern, with 39 million people living with the virus and 1.3 million new infections reported …
concern, with 39 million people living with the virus and 1.3 million new infections reported …
[HTML][HTML] Parainfluenza virus 5 priming followed by SIV/HIV virus-like-particle boosting induces potent and durable immune responses in nonhuman primates
The search for a preventive vaccine against HIV infection remains an ongoing challenge,
indicating the need for novel approaches. Parainfluenza virus 5 (PIV5) is a paramyxovirus …
indicating the need for novel approaches. Parainfluenza virus 5 (PIV5) is a paramyxovirus …