[HTML][HTML] The epidemiology of Alzheimer's disease modifiable risk factors and prevention

XX Zhang, Y Tian, ZT Wang, YH Ma, L Tan… - The journal of prevention …, 2021 - Springer
Mild Alzheimer's disease is the leading cause of dementia, accounting for 50–70% of cases.
Alzheimer's disease is an irreversible neurodegenerative disease, which affects daily life …

[HTML][HTML] Mechanisms and treatment of late-life depression

GS Alexopoulos - Translational psychiatry, 2019 - nature.com
Depression predisposes to medical illnesses and advances biological aging indicated by
shorter telomere length, accelerated brain aging and advanced epigenetic aging. Medical …

Dementia prevention, intervention, and care

G Livingston, A Sommerlad, V Orgeta, SG Costafreda… - The lancet, 2017 - thelancet.com
Executive summary Acting now on dementia prevention, intervention, and care will vastly
improve living and dying for individuals with dementia and their families, and in doing so …

[HTML][HTML] Depression—an underrecognized target for prevention of dementia in Alzheimer's disease

FS Dafsari, F Jessen - Translational Psychiatry, 2020 - nature.com
It is broadly acknowledged that the onset of dementia in Alzheimer's disease (AD) may be
modifiable by the management of risk factors. While several recent guidelines and …

Considering sex and gender in Alzheimer disease and other dementias

JL Podcasy, CN Epperson - Dialogues in clinical neuroscience, 2016 - Taylor & Francis
Suffering related to dementia is multifaceted because cognitive and physical functioning
slowly deteriorates. Advanced age and sex, two of the most prominent risk factors for …

[HTML][HTML] GABAergic inhibitory interneuron deficits in Alzheimer's disease: implications for treatment

Y Xu, M Zhao, Y Han, H Zhang - Frontiers in neuroscience, 2020 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disorder characterized clinically by severe
cognitive deficits and pathologically by amyloid plaques, neuronal loss, and neurofibrillary …

[HTML][HTML] Review of the neurological benefits of phytocannabinoids

J Maroon, J Bost - Surgical neurology international, 2018 - ncbi.nlm.nih.gov
Background: Numerous physical, psychological, and emotional benefits have been
attributed to marijuana since its first reported use in 2,600 BC in a Chinese pharmacopoeia …

Cannabidiol, neuroprotection and neuropsychiatric disorders

AC Campos, MV Fogaça, AB Sonego… - Pharmacological …, 2016 - Elsevier
Cannabidiol (CBD) is a non-psychotomimetic phytocannabinoid derived from Cannabis
sativa. It has possible therapeutic effects over a broad range of neuropsychiatric disorders …

[HTML][HTML] The role of serotonin within the microbiota-gut-brain axis in the development of Alzheimer's disease: A narrative review

E Aaldijk, Y Vermeiren - Ageing Research Reviews, 2022 - Elsevier
Alzheimer's disease (AD) is the most common cause of dementia, accounting for more than
50 million patients worldwide. Current evidence suggests the exact mechanism behind this …

[HTML][HTML] Chronic stress and glucocorticoids: from neuronal plasticity to neurodegeneration

S Vyas, AJ Rodrigues, JM Silva, F Tronche… - Neural …, 2016 - Wiley Online Library
Stress and stress hormones, glucocorticoids (GCs), exert widespread actions in central
nervous system, ranging from the regulation of gene transcription, cellular signaling …