Metal-based photosensitizers as inducers of regulated cell death mechanisms
Y Zhang, BT Doan, G Gasser - Chemical Reviews, 2023 - ACS Publications
Over the last few decades, various forms of regulated cell death (RCD) have been
discovered and were found to improve cancer treatment. Although there are several reviews …
discovered and were found to improve cancer treatment. Although there are several reviews …
Immunogenic cell death inducing metal complexes for cancer therapy
L Zhang, N Montesdeoca, J Karges… - Angewandte Chemie …, 2023 - Wiley Online Library
Cancer is one of the deadliest diseases worldwide. Recent statistics have shown that
metastases and tumor relapse are the leading causes of cancer‐associated deaths. While …
metastases and tumor relapse are the leading causes of cancer‐associated deaths. While …
Doping engineering to modulate lattice and electronic structure for enhanced piezocatalytic therapy and ferroptosis
B Tian, R Tian, S Liu, Y Wang, S Gai, Y Xie… - Advanced …, 2023 - Wiley Online Library
Piezocatalytic therapy, which generates reactive oxygen species (ROS) under mechanical
force, has garnered extensive attention for its use in cancer therapy owing to its deep tissue …
force, has garnered extensive attention for its use in cancer therapy owing to its deep tissue …
Near-infrared metal agents assisting precision medicine: from strategic design to bioimaging and therapeutic applications
C Li, Y Pang, Y Xu, M Lu, L Tu, Q Li… - Chemical Society …, 2023 - pubs.rsc.org
Metal agents have made incredible strides in preclinical research and clinical applications in
recent years, but their short emission/absorption wavelengths continue to be a barrier to …
recent years, but their short emission/absorption wavelengths continue to be a barrier to …
Engineering of BODIPY-based theranostics for cancer therapy
In recent years, BODIPY-based theranostics have increasingly been used in cancer therapy
and have achieved significant success. According to photochemical theories, the optical …
and have achieved significant success. According to photochemical theories, the optical …
Efficient NIR-II type-I AIE photosensitizer for mitochondria-targeted photodynamic therapy through synergistic apoptosis–ferroptosis
J Zhuang, B Wang, H Chen, K Zhang, N Li, N Zhao… - ACS …, 2023 - ACS Publications
Hypoxia, the hallmark of malignant tumors, has been recognized as a major obstacle for
photodynamic therapy (PDT). Precisely targeting cancer cells in intricate biological …
photodynamic therapy (PDT). Precisely targeting cancer cells in intricate biological …
Engineered metallacycle‐based supramolecular Photosensitizers for effective Photodynamic Therapy
Although metallacycle‐based supramolecular photosensitizers (PSs) have attracted
increasing attention in biomedicine, their clinical translation is still hindered by their inherent …
increasing attention in biomedicine, their clinical translation is still hindered by their inherent …
GSH/pH Dual Activatable Cross‐linked and Fluorinated PEI for Cancer Gene Therapy Through Endogenous Iron De‐Hijacking and in Situ ROS Amplification
Ferroptosis‐related cancer therapy is limited by insufficient Fe2+/Fe3+ redox pair and
hydrogen peroxide (H2O2) for producing lethal hydroxyl radicals (· OH). Although …
hydrogen peroxide (H2O2) for producing lethal hydroxyl radicals (· OH). Although …
A Metal‐Free Mesoporous Carbon Dots/Silica Hybrid Type I Photosensitizer with Enzyme‐Activity for Synergistic Treatment of Hypoxic Tumor
B Tian, S Liu, C Yu, S Liu, S Dong… - Advanced Functional …, 2023 - Wiley Online Library
As a less O2‐dependent photodynamic therapy (PDT), type I PDT is an effective approach to
overcome the hypoxia‐induced low efficiency against solid tumors. However, the commonly …
overcome the hypoxia‐induced low efficiency against solid tumors. However, the commonly …
When near-infrared fluorescence meets supramolecular coordination complexes: Challenges and opportunities of metallacycles/metallacages in precision …
Y Xu, Y Dou, Q Li, H Ye, Y Li, S Qiu, X Xiong, J Li… - Coordination Chemistry …, 2023 - Elsevier
In the past decade, the metallacycles/metallacages have attracted unremitting interest in
biomedical fields, yet visual tracking of their in vivo delivery, targeting ability, biodistribution …
biomedical fields, yet visual tracking of their in vivo delivery, targeting ability, biodistribution …