The Wnt/β-catenin pathway comprises a family of proteins that play critical roles in
embryonic development and adult tissue homeostasis. The deregulation of Wnt/β-catenin …

Cell differentiation, proliferation, and death are vital for immune homeostasis. Wnt signaling
plays essential roles in processes across species. The roles of Wnt signaling proteins and …

While platelets have long been known to be essential for maintaining hemostasis in the
vasculature, their role in tissue repair, inflammation and innate and adaptive immunity is a …

Apelin is an endogenous ligand of G protein-coupled receptor APJ. It is extensively
expressed in many tissues such as heart, liver, and kidney, especially in lung tissue. A …

Clinical and preclinical studies over the past 3 decades have uncovered a multitude of
signaling pathways involved in the initiation and progression of atherosclerosis. From these …

The Wnt signaling pathway is a conserved pathway involved in important cellular processes
such as the control of embryonic development, cellular polarity, cellular migration, and cell …

Background Schizophrenia (SCZ) and treatment-resistant schizophrenia (TRS) are
associated with aberrations in immune-inflammatory pathways. Increased high mobility …

Abstract In Primary Myelofibrosis (PMF), megakaryocyte dysplasia/hyperplasia determines
the release of inflammatory cytokines that, in turn, stimulate stromal cells and induce bone …

Acute lung injury (ALI) is an important cause of morbidity and mortality for critically ill
patients, and linarin (LR) may be a potential treatment for ALI as it reportedly has …

Recent findings have contributed to our burgeoning understanding of the platelet-dependent
mechanisms that control neutrophil recruitment to sites of inflammation and have opened up …