Substantial effort has been made over the last six decades to identify biomarkers for multiple
sclerosis that can improve disease diagnosis, predict disease progression, and improve …

Multiple sclerosis (MS) is a chronic neurodegenerative autoimmune disease with a complex
clinical course characterized by inflammation, demyelination, and axonal degeneration …

Since its initial identification as one of the genes most highly upregulated upon T-cell
activation, osteopontin (or Eta-1, as it was designated then) has been demonstrated to have …

Breakthroughs in the field of multiple sclerosis have led to a better understanding of the
physiopathology of the disease, follow up, and treatment of the patients that develop …

Multiple sclerosis (MS) is an immune mediated, inflammatory and demyelinating disease of
the central nervous system (CNS). Substantial evidence points toward monocytes and …

Osteopontin is a broadly expressed pleiotropic protein, and is attracting increased attention
because of its role in the pathophysiology of several inflammatory, degenerative …

Identifying a reliable biomarker may accelerate diagnosis of multiple sclerosis (MS) and lead
to early management of the disease. Accumulating evidence suggest that cerebrospinal fluid …

Multiple sclerosis (MS) is an autoimmune disease of unknown cause, in which chronic
inflammation drives multifocal demyelination of axons in both white and gray matter in the …

Osteopontin (OPN) is a multifunctional cytokine and adhesion molecule, as well as an
unusual regulator for both innate and adaptive immune responses. Several immune cells …

Introduction: Multiple Sclerosis (MS) is the most common immune-mediated chronic
neurodegenerative disease of the central nervous system (CNS) affecting young people …