Next-generation sequencing—an overview of the history, tools, and “Omic” applications

JK Kulski - Next generation sequencing-advances, applications …, 2016 - books.google.com
Next-generation sequencing (NGS) technologies using DNA, RNA, or methylation
sequencing have impacted enormously on the life sciences. NGS is the choice for large …

Whole cell biocatalysts: essential workers from nature to the industry

CCCR de Carvalho - Microbial Biotechnology, 2017 - Wiley Online Library
Microorganisms have been exposed to a myriad of substrates and environmental conditions
throughout evolution resulting in countless metabolites and enzymatic activities. Although …

Marine microorganisms as a promising and sustainable source of bioactive molecules

G Romano, M Costantini, C Sansone… - Marine environmental …, 2017 - Elsevier
There is an urgent need to discover new drug entities due to the increased incidence of
severe diseases as cancer and neurodegenerative pathologies, and reducing efficacy of …

[HTML][HTML] Metagenomics and artificial intelligence in the context of human health

AK Wani, P Roy, V Kumar - Infection, Genetics and Evolution, 2022 - Elsevier
Human microbiome is ubiquitous, dynamic, and site-specific consortia of microbial
communities. The pathogenic nature of microorganisms within human tissues has led to an …

Marine organisms as a rich source of biologically active peptides

MWFS Macedo, NB Cunha, JA Carneiro… - Frontiers in Marine …, 2021 - frontiersin.org
Oceanic environments are one of the largest sources of bioactive molecules, due to the high
degree of biodiversity and the innumerable ecological relationships established between …

Metagenomic applications in exploration and development of novel enzymes from nature: a review

FA Prayogo, A Budiharjo, HP Kusumaningrum… - Journal of Genetic …, 2020 - Springer
Background Microbial community has an essential role in various fields, especially the
industrial sector. Microbes produce metabolites in the form of enzymes, which are one of the …

Mining microbial tapestry using high-throughput sequencing and In silico analysis of Trehalose synthase (TreS) derived from hot spring metagenome

AK Wani, C Chopra, R Singh, S Ahmad… - Biocatalysis and …, 2023 - Elsevier
Understanding the microbial diversity and research trends using metagenomics is important
for biotechnological and environmental applications. In this study, we carried out bibliometric …

Screening concepts, characterization and structural analysis of microbial-derived bioactive lipopeptides: a review

P Biniarz, M Łukaszewicz, T Janek - Critical reviews in …, 2017 - Taylor & Francis
Lipopeptide biosurfactants are surface active biomolecules that are produced by a variety of
microorganisms. Microbial lipopeptides have gained the interest of microbiologists, chemists …

Shotgun metagenomics offers novel insights into taxonomic compositions, metabolic pathways and antibiotic resistance genes in fish gut microbiome

A Tyagi, B Singh, NK Billekallu Thammegowda… - Archives of …, 2019 - Springer
Gut microbiota of freshwater carp (Labeo rohita) was investigated by shotgun metagenomics
to understand its taxonomic composition and functional capabilities. With the presence of 36 …

CNN-MGP: convolutional neural networks for metagenomics gene prediction

A Al-Ajlan, A El Allali - Interdisciplinary Sciences: Computational Life …, 2019 - Springer
Accurate gene prediction in metagenomics fragments is a computationally challenging task
due to the short-read length, incomplete, and fragmented nature of the data. Most gene …