Familial hypercholesterolaemia (FH) is a common autosomal semi-dominant and highly
penetrant disorder of the low-density lipoprotein (LDL) receptor pathway, characterised by …

Abstract Lipoprotein (a)(Lp (a)) is associated with atherothrombosis through several
mechanisms, including putative antifibrinolytic properties. However, genetic association …

Genetics of Familial Hypercholesterolemia (FH) is ascribable to pathogenic variants in
genes encoding proteins leading to an impaired LDL uptake by the LDL receptor (LDLR) …

Background Despite its high prevalence and clinical significance, clinical measurement of
lipoprotein (a) is rare but has not been systematically quantified. We assessed the …

Calcific aortic valve stenosis (CAVS) is among the most common causes of cardiovascular
mortality in an aging population worldwide. The pathomechanisms of CAVS are such a …

Cardiovascular disease (CVD) remains the leading cause of death worldwide. Serum
lipoprotein (a)(Lp (a)) has been shown to be an independent and causative risk factor for …

Abstract Purpose Elevated lipoprotein (a)[Lp (a)] and diabetes mellitus (DM) are both
associated with adverse events in high-risk patients with established coronary artery …

Abstract Background and Aims Lipoprotein (a)(Lp [a]) is an established risk factor for
atherosclerotic cardiovascular disease (ASCVD). However, data on association of Lp (a) …

Abstract Background Lipoprotein (a)(Lp [a]) is a causal genetic risk factor for atherosclerotic
cardiovascular disease (ASCVD). There are limited long-term follow-up data from large US …

Statins have contributed to the prevention of numerous atherosclerotic cardiovascular (CV)
events and cardiovascular deaths in the past three decades. The benefit of statins is mainly …