[HTML][HTML] The role of tumor-associated macrophages in lung cancer: From mechanism to small molecule therapy
Y Zhou, M Qian, J Li, L Ruan, Y Wang, C Cai… - Biomedicine & …, 2024 - Elsevier
Tumor-associated macrophages (TAMs) are the main component of tumor-infiltrating
immune cells in the lung tumor microenvironment. TAMs recruited to the lung cancer can …
immune cells in the lung tumor microenvironment. TAMs recruited to the lung cancer can …
[HTML][HTML] Leveraging macrophage metabolism for anticancer therapy: opportunities and pitfalls
P Saha, P Ettel, T Weichhart - Trends in Pharmacological Sciences, 2024 - cell.com
Tumor-associated macrophages (TAMs) constitute an important part of the tumor
microenvironment (TME) that regulates tumor progression. Tumor-derived signals, hypoxia …
microenvironment (TME) that regulates tumor progression. Tumor-derived signals, hypoxia …
SBFI26 induces triple‐negative breast cancer cells ferroptosis via lipid peroxidation
G He, Y Zhang, Y Feng, T Chen, M Liu… - Journal of Cellular …, 2024 - Wiley Online Library
SBFI26, an inhibitor of FABP5, has been shown to suppress the proliferation and metastasis
of tumour cells. However, the underlying mechanism by which SBFI26 induces ferroptosis in …
of tumour cells. However, the underlying mechanism by which SBFI26 induces ferroptosis in …
[HTML][HTML] Revealing the role of SPP1+ macrophages in glioma prognosis and therapeutic targeting by investigating tumor-associated macrophage landscape in grade …
W Tang, CWS Lo, W Ma, ATW Chu, AHY Tong… - Cell & Bioscience, 2024 - Springer
Background Glioma is a highly heterogeneous brain tumor categorized into World Health
Organization (WHO) grades 1–4 based on its malignancy. The suppressive immune …
Organization (WHO) grades 1–4 based on its malignancy. The suppressive immune …
Fatty acid binding protein 5 suppression attenuates obesity-induced hepatocellular carcinoma by promoting ferroptosis and intratumoral immune rewiring
J Sun, E Esplugues, A Bort, MP Cardelo… - Nature …, 2024 - nature.com
Due to the rise in overnutrition, the incidence of obesity-induced hepatocellular carcinoma
(HCC) will continue to escalate; however, our understanding of the obesity to HCC …
(HCC) will continue to escalate; however, our understanding of the obesity to HCC …
From monocyte‐derived macrophages to resident macrophages—how metabolism leads their way in cancer
U Ammarah, A Pereira‐Nunes, M Delfini… - Molecular …, 2024 - Wiley Online Library
Macrophages are innate immune cells that play key roles during both homeostasis and
disease. Depending on the microenvironmental cues sensed in different tissues …
disease. Depending on the microenvironmental cues sensed in different tissues …
Engineered lactococcus lactis intrapleural therapy promotes regression of malignant pleural effusion by enhancing antitumor immunity
Y Fan, A Chen, J Zhu, R Liu, Y Mei, L Li, X Sha… - Cancer Letters, 2024 - Elsevier
Intrapleural immunotherapies have emerged as a prominent field in treating malignant
pleural effusion (MPE). Among these, bacteria-based intrapleural therapy has exerted an …
pleural effusion (MPE). Among these, bacteria-based intrapleural therapy has exerted an …
Single‐cell RNA sequencing reveals aberrant sphingolipid metabolism in non‐small cell lung cancer impacts tumor‐associated macrophages and stimulates …
L Shen, J Liu, F Hu, Y Fang, Y Wu, W Zhao… - Thoracic …, 2024 - Wiley Online Library
Background Sphingolipids not only serve as structural components for maintaining cell
membrane fluidity but also function as bioactive molecules involved in cell signaling and the …
membrane fluidity but also function as bioactive molecules involved in cell signaling and the …
[HTML][HTML] 外周血总胆汁酸, 补体C1q 以及体重指数与胆汁反流性胃炎伴肠上皮化生关系的研究
刘静依， 魏朝晗， 张文姣， 解祥军 - Advances in Clinical Medicine, 2024 - hanspub.org
目的: 评价外周血的总胆汁酸(total bile acid, TBA), 补体C1q (complement C1q)
水平以及体重指数(body mass index, BMI) 对胆汁反流性胃炎(bile reflux gastritis, BRG) …
水平以及体重指数(body mass index, BMI) 对胆汁反流性胃炎(bile reflux gastritis, BRG) …