Human brain evolution: transcripts, metabolites and their regulators

M Somel, X Liu, P Khaitovich - Nature Reviews Neuroscience, 2013 - nature.com
What evolutionary events led to the emergence of human cognition? Although the genetic
differences separating modern humans from both non-human primates (for example …

Old trade, new tricks: insights into the spontaneous mutation process from the partnering of classical mutation accumulation experiments with high-throughput …

V Katju, U Bergthorsson - Genome Biology and Evolution, 2019 - academic.oup.com
Mutations spawn genetic variation which, in turn, fuels evolution. Hence, experimental
investigations into the rate and fitness effects of spontaneous mutations are central to the …

The rise of genomics in snake venom research: recent advances and future perspectives

W Rao, K Kalogeropoulos, ME Allentoft… - …, 2022 - academic.oup.com
Snake venoms represent a danger to human health, but also a gold mine of bioactive
proteins that can be harnessed for drug discovery purposes. The evolution of snakes and …

A comparison of gene expression and DNA methylation patterns across tissues and species

LE Blake, J Roux, I Hernando-Herraez… - Genome …, 2020 - genome.cshlp.org
Previously published comparative functional genomic data sets from primates using frozen
tissue samples, including many data sets from our own group, were often collected and …

Genomic insights into selection for heterozygous alleles and woody traits in Populus tomentosa

P Li, L Xiao, Q Du, M Quan, Y Song… - Plant Biotechnology …, 2023 - Wiley Online Library
Heterozygous alleles are widespread in outcrossing and clonally propagated woody plants.
The variation in heterozygosity that underlies population adaptive evolution and phenotypic …

[HTML][HTML] Data mining in healthcare: Applying strategic intelligence techniques to depict 25 years of research development

ML Kolling, LB Furstenau, MK Sott, B Rabaioli… - International journal of …, 2021 - mdpi.com
In order to identify the strategic topics and the thematic evolution structure of data mining
applied to healthcare, in this paper, a bibliometric performance and network analysis …

Comparative analysis of gene regulatory networks: from network reconstruction to evolution

D Thompson, A Regev, S Roy - Annual review of cell and …, 2015 - annualreviews.org
Regulation of gene expression is central to many biological processes. Although
reconstruction of regulatory circuits from genomic data alone is therefore desirable, this …

Evolution of genetic and genomic features unique to the human lineage

M O'bleness, VB Searles, A Varki, P Gagneux… - Nature Reviews …, 2012 - nature.com
Given the unprecedented tools that are now available for rapidly comparing genomes, the
identification and study of genetic and genomic changes that are unique to our species have …

Targeted genome-modification tools and their advanced applications in crop breeding

B Li, C Sun, J Li, C Gao - Nature Reviews Genetics, 2024 - nature.com
Crop improvement by genome editing involves the targeted alteration of genes to improve
plant traits, such as stress tolerance, disease resistance or nutritional content. Techniques …

Single-cell dissection of aggression in honeybee colonies

IM Traniello, SA Bukhari, P Dibaeinia… - Nature Ecology & …, 2023 - nature.com
Understanding how genotypic variation results in phenotypic variation is especially difficult
for collective behaviour because group phenotypes arise from complex interactions among …