As a main digestive organ and an important immune organ, the intestine plays a vital role in
resisting the invasion of potential pathogens into the body. Intestinal immune dysfunction …

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with poor patient
survival. Toward understanding the underlying molecular alterations that drive PDAC …

The glutaminolysis and serine–glycine–one-carbon pathways represent metabolic reactions
that are reprogramed and upregulated in cancer; these pathways are involved in supporting …

Long non-coding RNA LIFR-AS1 is low-expressed in many cancers, but its functions in
papillary thyroid carcinoma (PTC) were not defined and require further study. The …

Background. Ulcerative colitis (UC) is a chronic inflammatory disease with increasing
prevalence worldwide. Barrier defect in intestinal epithelial cells (IECs) is one of the main …

Background Pancreatic ductal adenocarcinoma (PDAC) has the worst five-year overall
survival rate among all cancer types. Acquired chemoresistance is considered one of the …

Simple Summary Pancreatic cancer is a highly lethal malignancy. Dysregulation of
epigenetic mechanisms leads to abnormal patterns of gene expression contributing to the …

Abstract Background Tumor‐educated platelets (TEPs) may enable blood‐based cancer
diagnosis. This study aimed to identify diagnostic TEPs genes involved in carcinogenesis …

Background Breast cancer (BC) is a leading cause of mortality among women, underscoring
the urgent need for improved therapeutic predictio. Developing a precise prognostic model …

Abstract Cyanogramide (AC14), a novel alkaloid, isolated from the fermentation broth of the
marine-derived Actinoalloteichus cyanogriseus. However, the exact role of AC14 in …