Bovine lactoferrin-derived ACE inhibitory tripeptide LRP also shows antioxidative and anti-inflammatory activities in endothelial cells

Y Gu, J Wu - Journal of Functional Foods, 2016 - Elsevier
The pathophysiology of hypertension involves the interplay among renin-angiotensin system
(RAS), oxidative stress and inflammation. Our previous computational study has indicated …

Antibacterial activity of bovine milk lactoferrin and its hydrolysates prepared with pepsin, chymosin and microbial rennet against foodborne pathogen Listeria …

D Ripolles, S Harouna, JA Parrón, M Calvo… - International Dairy …, 2015 - Elsevier
Lactoferrin is an iron binding glycoprotein that contains antimicrobial peptides in its
structure, which are released when hydrolysed by proteases. The antibacterial activity of …

Casein Hydrolysates by Lactobacillus brevis and Lactococcus lactis Proteases: Peptide Profile Discriminates Strain-Dependent Enzyme Specificity

FZ Bounouala, S Roudj, NE Karam… - Journal of agricultural …, 2017 - ACS Publications
Casein from ovine and bovine milk were hydrolyzed with two extracellular protease
preparations from Lactobacillus brevis and Lactococcus lactis. The hydrolysates were …

Dairy yeasts produce milk protein-derived antihypertensive hydrolysates

A García-Tejedor, B Padilla, JB Salom… - Food Research …, 2013 - Elsevier
The potential of 20 dairy yeast strains belonging to Debaryomyces hansenii, Kluyveromyces
lactis and Kluyveromyces marxianus species was examined for the production of milk …

Identification of dual-function bovine lactoferrin peptides released using simulated gastrointestinal digestion

M Tu, S Xu, Z Xu, S Cheng, D Wu, H Liu, M Du - Food Bioscience, 2021 - Elsevier
Lactoferrin (LF) is a good protein for producing various bioactive peptides, such as those
with antimicrobial, immunomodulating, and antihypertensive activities. However, there is no …

Low-molecular weight peptides isolated from seahorse (Hippocampus abdominalis) improve vasodilation via inhibition of angiotensin-converting enzyme in vivo and …

JG Je, HS Kim, HG Lee, JY Oh, YA Lu, L Wang… - Process …, 2020 - Elsevier
According to relevant literature, the consumption of seahorses has been used to increase
male functions by improving blood flow and decreasing blood pressure. Thus, it was …

Structural basis of bioactivity of food peptides in promoting metabolic health

S Yao, D Agyei, CC Udenigwe - Advances in food and nutrition Research, 2018 - Elsevier
Bioactive peptides have many structural features that enable them to become functional in
controlling several biological processes in the body, especially those related to metabolic …

The production of bioactive peptides from milk proteins

T Kleekayai, M Cermeño, RJ FitzGerald - … of Change: Enzymes in Milk and …, 2021 - Springer
Peptides derived from milk proteins are associated with a range of different bioactivities, eg,
antioxidant, antihypertensive, antidiabetic, immunomodulatory, antimicrobial, opioid …

Prediction of drug positioning for quan-du-zhong capsules against hypertensive nephropathy based on the robustness of disease network

F Guo, W Zhang, J Su, H Xu, H Yang - Frontiers in Pharmacology, 2019 - frontiersin.org
Hypertensive nephropathy (HN) is a medical condition in which chronic high blood pressure
causes different kidney damage, including vascular, glomerular and tubulointerstitial …

Hypotensive and Vasorelaxant Effects of Sericin‐Derived Oligopeptides in Rats

A Onsa-Ard, D Shimbhu, J Tocharus… - International …, 2013 - Wiley Online Library
Sericin‐derived oligopeptides obtained from silk cocoons were investigated for the in vivo
hypotensive effect and investigated for the underlying mechanism involved in vasodilation in …