Background: Animal spinal cord injury (SCI) models have proved invaluable in better
understanding the mechanisms involved in traumatic SCI and evaluating the effectiveness of …

Simple Summary This review highlights the scope of available treatment options for
neurological diseases, especially stem cell transplantation therapy, which provides new …

Cell transplantation, as a therapeutic intervention for spinal cord injury (SCI), has been
extensively studied by researchers in recent years. A number of different kinds of stem cells …

More than 1 million people in the United States live with a spinal cord injury (SCI). Despite
medical advances, many patients with SCIs still experience substantial neurological …

Geron recently announced that it had begun enrolling patients in the world's first-in-human
clinical trial involving cells derived from human embryonic stem cells (hESCs). This trial …

The pathology of spinal cord injury (SCI) makes it appropriate for cell-based therapies.
Treatments using neural stem cells (NSCs) in animal models of SCI have shown positive …

Cervical spinal cord injury (SCI) remains a devastating event without adequate treatment
options despite decades of research. In this context, the usefulness of common preclinical …

The spinal cord injury leads to enervation of normal tissue homeostasis ultimately leading to
paralysis. Until now there is no proper cure for the treatment of spinal cord injury. Recently …

Inflammatory response following spinal cord injury (SCI) is important in regulation of the
repair process. Olfactory ensheathing cells (OECs) and Schwann cells (SCs) are important …

Spinal cord injury has a significant societal and personal impact. Although the majority of
injuries involve the cervical spinal cord, few studies of cell transplantation have used …