Quantitative characterization of population-wide tissue-and metabolite-specific variability in perchloroethylene toxicokinetics in male mice
Quantification of interindividual variability is a continuing challenge in risk assessment,
particularly for compounds with complex metabolism and multi-organ toxicity. Toxicokinetic …
particularly for compounds with complex metabolism and multi-organ toxicity. Toxicokinetic …
Urinary trichloroacetic acid and high blood pressure: A cross-sectional study of general adults in Shijiazhuang, China
S Zhang, A Guo, J Gu, R Zhang, N Wei - Environmental Research, 2019 - Elsevier
Exposure to trichloroacetic acid (TCAA) and its parent chemicals potentially linked to
cardiovascular disease. However, the association between TCAA and blood pressure (BP) …
cardiovascular disease. However, the association between TCAA and blood pressure (BP) …
PBPK modeling of impact of nonalcoholic fatty liver disease on toxicokinetics of perchloroethylene in mice
Background Nonalcoholic fatty liver disease (NAFLD), a major cause of chronic liver disease
in the Western countries with increasing prevalence worldwide, may substantially affect …
in the Western countries with increasing prevalence worldwide, may substantially affect …
Modulation of tetrachloroethylene-associated kidney effects by nonalcoholic fatty liver or steatohepatitis in male C57BL/6J mice
JA Cichocki, YS Luo, S Furuya… - Toxicological …, 2019 - academic.oup.com
Accounting for genetic and other (eg, underlying disease states) factors that may lead to
inter-individual variability in susceptibility to xenobiotic-induced injury is a challenge in …
inter-individual variability in susceptibility to xenobiotic-induced injury is a challenge in …
[图书][B] Microcystin-LR Hepatic and Renal Toxicity in Nonalcoholic Fatty Liver Disease
T Arman - 2021 - search.proquest.com
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the
United States. Up to 54% of patients with a severe form of NAFLD, called nonalcoholic …
United States. Up to 54% of patients with a severe form of NAFLD, called nonalcoholic …
[HTML][HTML] Role of diet and xenobiotics in the progression of nonalcoholic fatty liver disease
X Li - 2018 - search.proquest.com
Non-alcoholic fatty liver disease (NAFLD) has become the leading cause of chronic liver
disease. The spectrum of NAFLD ranges from simple steatosis, to non-alcoholic …
disease. The spectrum of NAFLD ranges from simple steatosis, to non-alcoholic …
[PDF][PDF] TSCA Scientific Advisory Committee on Chemicals
A Dunn, D Fischer, T Henry, M Hartman, S Barone… - 2020 - files.chemicalwatch.com
The Toxic Substances Control Act (TSCA) of 1976, as amended by The Frank R. Lautenberg
Chemical Safety for the 21st Century Act in 2016, Science Advisory Committee on …
Chemical Safety for the 21st Century Act in 2016, Science Advisory Committee on …
[PDF][PDF] EPA'S IRIS PROGRAM: REVIEWING ITS PROGRESS AND ROADBLOCKS AHEAD
I Rusyn - 2019 - science.house.gov
As a matter of full disclosure pertaining to the topic of today's hearings, I am currently
chairing a Workshop Committee of the National Academies of Sciences, Engineering & …
chairing a Workshop Committee of the National Academies of Sciences, Engineering & …