The host response to biomaterials has been studied for decades. Largely, the interaction of
host immune cells, macrophages in particular, with implanted materials has been …

Atherosclerosis is the main pathological basis for the occurrence of most cardiovascular
diseases, the leading global health threat, and a great burden for society. It has been well …

Chronic inflammation drives atherosclerosis, the leading cause of cardiovascular disease.
Over the past two decades, data have emerged showing that immune cells are involved in …

Matrix metalloproteinases (MMPs), also called matrixins, function in the extracellular
environment of cells and degrade both matrix and non-matrix proteins. They play central …

Neurodegeneration is the pathological condition, in which the nervous system or neuron
loses its structure, function, or both, leading to progressive degeneration or the death of …

Atherosclerosis is a chronic inflammatory disease of the arterial wall driven by innate and
adaptive immune responses. Inflammation controls the development and the destabilization …

Atherosclerosis is an inflammatory disease of the wall of large-and medium-sized arteries
that is precipitated by elevated levels of low-density lipoprotein (LDL) cholesterol in the …

Atherosclerosis is a chronic disease of the arterial wall where both innate and adaptive
immunoinflammatory mechanisms are involved. Inflammation is central at all stages of …

Plasma free fatty acid (FFA) levels are elevated in obesity. FFAs cause insulin resistance in
all major insulin target organs (skeletal muscle, liver, endothelial cells) and have emerged …

Matrix metalloproteinases (MMPs) are now acknowledged as key players in the regulation of
both cell–cell and cell–extracellular matrix interactions. They are involved in modifying …