In contrast to nitric oxide, which has well established and important roles in the regulation of
blood flow and thrombosis, neurotransmission, the normal functioning of the genitourinary …

Process of inflammation and complex interactions between immune and cancer cells within
tumor microenvironment are known to drive and shape the outcome of the neoplastic …

The prevalence of heart failure (HF) due to cardiac remodelling after acute myocardial
infarction (AMI) does not decrease regardless of implementation of new technologies …

Background: Redox signaling plays an important role in the lives of cells. This signaling not
only becomes apparent in pathologies but is also thought to be involved in maintaining …

The endothelial cells (ECs) make up the inner lining of blood vessels, acting as a barrier
separating the blood and the tissues in several organs. ECs maintain endothelium integrity …

Purpose of review Ionizing radiation is a highly effective treatment for a wide range of
malignancies, yet the cardiovascular (CV) toxicity that can result from chest radiotherapy …

The field of mitochondrial ion channels underwent a rapid development during the last
decade, thanks to the molecular identification of some of the nuclear-encoded organelle …

The large-conductance calcium-and voltage-activated K+ channel (BKCa) are encoded by
the Kcnma1 gene. They are ubiquitously expressed in neuronal, smooth muscle, astrocytes …

Ischemic diseases in an aging population pose a heavy social encumbrance. Moreover,
current therapeutic approaches, which aimed to prevent or minimize ischemia-induced …

Gender difference is well recognized as a key risk factor for cardiovascular disease (CVD).
Estrogen, the primary female sex hormone, improves cardiovascular functions through …