Diffuse optics for tissue monitoring and tomography

T Durduran, R Choe, WB Baker… - Reports on progress in …, 2010 - iopscience.iop.org
This review describes the diffusion model for light transport in tissues and the medical
applications of diffuse light. Diffuse optics is particularly useful for measurement of tissue …

Multifunctional nanoparticles for drug delivery and molecular imaging

G Bao, S Mitragotri, S Tong - Annual review of biomedical …, 2013 - annualreviews.org
Recent advances in nanotechnology and growing needs in biomedical applications have
driven the development of multifunctional nanoparticles. These nanoparticles, through …

ReaChR: a red-shifted variant of channelrhodopsin enables deep transcranial optogenetic excitation

JY Lin, PM Knutsen, A Muller, D Kleinfeld… - Nature …, 2013 - nature.com
Channelrhodopsins (ChRs) are used to optogenetically depolarize neurons. We engineered
a variant of ChR, denoted red-activatable ChR (ReaChR), that is optimally excited with …

Intraoperative tissue identification using rapid evaporative ionization mass spectrometry

J Balog, L Sasi-Szabó, J Kinross, MR Lewis… - Science translational …, 2013 - science.org
Rapid evaporative ionization mass spectrometry (REIMS) is an emerging technique that
allows near–real-time characterization of human tissue in vivo by analysis of the aerosol …

Image-guided surgery using invisible near-infrared light: fundamentals of clinical translation

S Gioux, HS Choi, JV Frangioni - Molecular imaging, 2010 - journals.sagepub.com
The field of biomedical optics has matured rapidly over the last decade and is poised to
make a significant impact on patient care. In particular, wide-field (typically> 5 cm), planar …

Advanced time-correlated single photon counting techniques for spectroscopy and imaging in biomedical systems

W Becker, A Bergmann, GL Biscotti… - … Applications of Ultrafast …, 2004 - spiedigitallibrary.org
Time-correlated single photon counting (TCSPC) is based on the detection of single photons
of a periodic light signal, measurement of the detection time of the photons, and the build-up …

[HTML][HTML] Imaging and cancer: a review

L Fass - Molecular oncology, 2008 - Elsevier
Multiple biomedical imaging techniques are used in all phases of cancer management.
Imaging forms an essential part of cancer clinical protocols and is able to furnish …

Molecular imaging in drug discovery and development

M Rudin, R Weissleder - Nature reviews Drug discovery, 2003 - nature.com
Imaging sciences have grown exponentially during the past three decades, and many
techniques, such as magnetic resonance imaging, nuclear tomographic imaging and X-ray …

Fluorescence molecular imaging

V Ntziachristos - Annu. Rev. Biomed. Eng., 2006 - annualreviews.org
There is a wealth of new fluorescent reporter technologies for tagging of many cellular and
subcellular processes in vivo. This imposed contrast is now captured with an increasing …

Bimolecular fluorescence complementation (BiFC) analysis: advances and recent applications for genome-wide interaction studies

KE Miller, Y Kim, WK Huh, HO Park - Journal of molecular biology, 2015 - Elsevier
Complex protein networks are involved in nearly all cellular processes. To uncover these
vast networks of protein interactions, various high-throughput screening technologies have …