Range uncertainties in proton therapy and the role of Monte Carlo simulations

H Paganetti - Physics in Medicine & Biology, 2012 - iopscience.iop.org
The main advantages of proton therapy are the reduced total energy deposited in the patient
as compared to photon techniques and the finite range of the proton beam. The latter adds …

Nuclear physics in particle therapy: a review

M Durante, H Paganetti - Reports on Progress in Physics, 2016 - iopscience.iop.org
Charged particle therapy has been largely driven and influenced by nuclear physics. The
increase in energy deposition density along the ion path in the body allows reducing the …

TOPAS: an innovative proton Monte Carlo platform for research and clinical applications

J Perl, J Shin, J Schümann, B Faddegon… - Medical …, 2012 - Wiley Online Library
Purpose: While Monte Carlo particle transport has proven useful in many areas (treatment
head design, dose calculation, shielding design, and imaging studies) and has been …

In vivo proton range verification: a review

AC Knopf, A Lomax - Physics in Medicine & Biology, 2013 - iopscience.iop.org
Protons are an interesting modality for radiotherapy because of their well defined range and
favourable depth dose characteristics. On the other hand, these same characteristics lead to …

[HTML][HTML] The FLUKA code: an accurate simulation tool for particle therapy

G Battistoni, J Bauer, TT Boehlen, F Cerutti… - Frontiers in …, 2016 - frontiersin.org
Monte Carlo (MC) codes are increasingly spreading in the hadrontherapy community due to
their detailed description of radiation transport and interaction with matter. The suitability of a …

A phenomenological relative biological effectiveness (RBE) model for proton therapy based on all published in vitro cell survival data

AL McNamara, J Schuemann… - Physics in Medicine & …, 2015 - iopscience.iop.org
Proton therapy treatments are currently planned and delivered using the assumption that the
proton relative biological effectiveness (RBE) relative to photons is 1.1. This assumption …

[图书][B] Proton therapy physics

H Paganetti - 2018 - books.google.com
Expanding on the highly successful first edition, this second edition of Proton Therapy
Physics has been completely restructured and updated throughout, and includes several …

MR-guided proton therapy: a review and a preview

A Hoffmann, B Oborn, M Moteabbed, S Yan… - Radiation …, 2020 - Springer
Background The targeting accuracy of proton therapy (PT) for moving soft-tissue tumours is
expected to greatly improve by real-time magnetic resonance imaging (MRI) guidance. The …

Range uncertainty in proton therapy due to variable biological effectiveness

A Carabe, M Moteabbed, N Depauw… - Physics in Medicine …, 2012 - iopscience.iop.org
Traditionally, dose in proton radiotherapy is prescribed as Gy (RBE) by scaling up the
physical dose by 10%. The relative biological effectiveness (RBE) of protons is considered …

Dual-energy CT based mass density and relative stopping power estimation for proton therapy using physics-informed deep learning

CW Chang, Y Gao, T Wang, Y Lei… - Physics in Medicine …, 2022 - iopscience.iop.org
Proton therapy requires accurate dose calculation for treatment planning to ensure the
conformal doses are precisely delivered to the targets. The conversion of CT numbers to …