Validation of a deep learning-based material estimation model for Monte Carlo dose calculation in proton therapy

CW Chang, S Zhou, Y Gao, L Lin, T Liu… - Physics in Medicine …, 2022 - iopscience.iop.org
Objective. Computed tomography (CT) to material property conversion dominates proton
range uncertainty, impacting the quality of proton treatment planning. Physics-based and …

GPU-based fast Monte Carlo dose calculation for proton therapy

X Jia, J Schümann, H Paganetti… - Physics in Medicine & …, 2012 - iopscience.iop.org
Accurate radiation dose calculation is essential for successful proton radiotherapy. Monte
Carlo (MC) simulation is considered to be the most accurate method. However, the long …

A stoichiometric calibration method for dual energy computed tomography

AE Bourque, JF Carrier… - Physics in Medicine & …, 2014 - iopscience.iop.org
The accuracy of radiotherapy dose calculation relies crucially on patient composition data.
The computed tomography (CT) calibration methods based on the stoichiometric calibration …

A Monte Carlo pencil beam scanning model for proton treatment plan simulation using GATE/GEANT4

L Grevillot, D Bertrand, F Dessy, N Freud… - Physics in Medicine & …, 2011 - iopscience.iop.org
This work proposes a generic method for modeling scanned ion beam delivery systems,
without simulation of the treatment nozzle and based exclusively on beam data library (BDL) …

Variations in linear energy transfer within clinical proton therapy fields and the potential for biological treatment planning

C Grassberger, A Trofimov, A Lomax… - International Journal of …, 2011 - Elsevier
PURPOSE: To calculate the linear energy transfer (LET) distributions in patients undergoing
proton therapy. These distributions can be used to identify areas of elevated or diminished …

Focused VHEE (very high energy electron) beams and dose delivery for radiotherapy applications

L Whitmore, RI Mackay, M Van Herk, JK Jones… - Scientific Reports, 2021 - nature.com
This paper presents the first demonstration of deeply penetrating dose delivery using
focused very high energy electron (VHEE) beams using quadrupole magnets in Monte Carlo …

Monte Carlo patient study on the comparison of prompt gamma and PET imaging for range verification in proton therapy

M Moteabbed, S Espana… - Physics in Medicine & …, 2011 - iopscience.iop.org
The purpose of this work was to compare the clinical adaptation of prompt gamma (PG)
imaging and positron emission tomography (PET) as independent tools for non-invasive …

Precision radiotherapy for non-small cell lung cancer

WC Yang, FM Hsu, PC Yang - Journal of Biomedical Science, 2020 - Springer
Precision medicine is becoming the standard of care in anti-cancer treatment. The
personalized precision management of cancer patients highly relies on the improvement of …

Benchmarking nuclear models of FLUKA and GEANT4 for carbon ion therapy

TT Böhlen, F Cerutti, M Dosanjh, A Ferrari… - Physics in Medicine …, 2010 - iopscience.iop.org
As carbon ions, at therapeutic energies, penetrate tissue, they undergo inelastic nuclear
reactions and give rise to significant yields of secondary fragment fluences. Therefore, an …

Interplay effects in proton scanning for lung: a 4D Monte Carlo study assessing the impact of tumor and beam delivery parameters

S Dowdell, C Grassberger, GC Sharp… - Physics in Medicine & …, 2013 - iopscience.iop.org
Relative motion between a tumor and a scanning proton beam results in a degradation of
the dose distribution (interplay effect). This study investigates the relationship between beam …