Pirfenidone and post-Covid-19 pulmonary fibrosis: invoked again for realistic goals

HM Al-Kuraishy, GES Batiha, H Faidah… - …, 2022 - Springer
Pirfenidone (PFN) is an anti-fibrotic drug with significant anti-inflammatory property used for
treatment of fibrotic conditions such as idiopathic pulmonary fibrosis (IPF). In the coronavirus …

A potential link between visceral obesity and risk of Alzheimer's disease

HM Al-Kuraishy, AI Al-Gareeb, AA Alsayegh… - Neurochemical …, 2023 - Springer
Alzheimer's disease (AD) is the most common type of dementia characterized by the
deposition of amyloid beta (Aβ) plaques and tau-neurofibrillary tangles in the brain. Visceral …

Statins use in Alzheimer disease: bane or boon from frantic search and narrative review

N Alsubaie, HM Al-Kuraishy, AI Al-Gareeb, B Alharbi… - Brain sciences, 2022 - mdpi.com
Alzheimer's disease (AD) was used to describe pre-senile dementia to differentiate it from
senile dementia, which develops in the adult age group of more than 65 years. AD is …

The potential role of growth differentiation factor 15 in COVID-19: a corollary subjective effect or not?

AO Babalghith, HM Al-Kuraishy, AI Al-Gareeb… - Diagnostics, 2022 - mdpi.com
Coronavirus disease 2019 (COVID-19) is primarily caused by various forms of severe acute
respiratory syndrome coronavirus type 2 (SARS-CoV-2) variants. COVID-19 is characterized …

Montelukast and acute coronary syndrome: the endowed drug

BM Alomair, HM Al-Kuraishy, AI Al-Gareeb… - Pharmaceuticals, 2022 - mdpi.com
Acute coronary syndrome (ACS) is a set of signs and symptoms caused by a reduction of
coronary blood flow with subsequent myocardial ischemia. ACS is associated with activation …

The potential therapeutic effect of phosphodiesterase 5 inhibitors in the acute ischemic stroke (AIS)

R AlRuwaili, HM Al-Kuraishy, M Alruwaili… - Molecular and Cellular …, 2023 - Springer
Acute ischemic stroke (AIS) is a focal neurological disorder that accounts for 85% of all
stroke types, due to occlusion of cerebral arteries by thrombosis and emboli. AIS is also …

[HTML][HTML] SARS-CoV-2 infection and dysregulation of nuclear factor erythroid-2-related factor 2 (Nrf2) pathway

RS Hamad, HM Al-Kuraishy, A Alexiou… - Cell Stress and …, 2023 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a recent pandemic caused by a novel
severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) leading to pulmonary and …

Pregnancy and COVID-19: high or low risk of vertical transmission

HM Al-Kuraishy, AI Al-Gareeb, NKA Albezrah… - Clinical and …, 2023 - Springer
Abstract Coronavirus disease 19 (COVID-19) is an infectious disease caused by severe
acute respiratory syndrome 2 (SARS-CoV-2). Throughout the pandemic, evidence on the …

Promising hepatoprotective agents from the natural sources: a study of scientific evidence

B Pandey, R Baral, A Kaundinnyayana, S Panta - Egyptian Liver Journal, 2023 - Springer
Background Natural bioactive components derived from plant secondary metabolites have
been pronounced as valuable alternatives for anticipating and subsiding hepatotoxic effects …

Roxadustat for SARS-CoV-2 infection: old signaling raised new hopes

L Alkazmi, HM Al-Kuraishy, GES Batiha… - Drugs in R&D, 2022 - Springer
Roxadustat (RXT)(4-hydroxyl-1-methyl-7-phenoxyisoquinoline-3-caboxylic acid)(Fig. 1) is
an orally active prolyl hydroxylase (PHD) inhibitor that increases production of endogenous …