Drug resistance is a major challenge in cancer treatment. Emerging evidence indicates that
deregulation of YAP/TAZ signaling may be a major mechanism of intrinsic and acquired …

Pancreatic cancer is one of the most common causes of cancer death in the world due to the
lack of early symptoms, metastasis occurrence and chemoresistance. Therefore, early …

Pancreatic ductal adenocarcinoma (PDAC) has one of the highest mortality rates among all
cancer types. Its delayed diagnosis precludes curative resection, thus most of the current …

Background Chemoresistance is one of the main causes of poor prognosis in pancreatic
cancer patients. Understanding the mechanisms implicated in chemoresistance of …

Long non-coding RNAs (lncRNAs) have shown potential as a biomarker in the diagnosis
and prognosis in multiple cancers. LncRNAs are dysregulated in various cancers, playing …

Background Circular RNAs (circRNAs) play an important role in the tumorigenesis of
pancreatic cancer. However, the expression profiles and roles of circRNAs in pancreatic …

Pancreatic cancer is a malignant disease that develops rapidly and carries a poor
prognosis. Currently, surgery is the only radical treatment. Non‑coding RNAs (ncRNAs) are …

Although long noncoding RNAs (lncRNAs) do not have protein coding capacities, they are
involved in the pathogenesis of many types of cancers, including hepatocellular carcinoma …

Long non-coding RNAs (lncRNAs) are emerging regulators of a diverse range of biological
processes through various mechanisms. Genome-wide association studies of tumor …

BACKGROUND Gastric cancer is a prevalent malignant cancer with a high incidence and
significantly affects the health of modern people globally. Cisplatin (DDP) is one of the most …