Simulating nature in sperm selection for assisted reproduction
ETY Leung, CL Lee, X Tian, KKW Lam, RHW Li… - Nature Reviews …, 2022 - nature.com
Sperm selection in the female reproductive tract (FRT) is sophisticated. Only about 1,000
sperm out of millions in an ejaculate reach the fallopian tube and thus have a chance of …
sperm out of millions in an ejaculate reach the fallopian tube and thus have a chance of …
[HTML][HTML] Microneedle arrays integrated with living organisms for smart biomedical applications
B Cai, Y Gong, Z Wang, L Wang, W Chen - Theranostics, 2021 - ncbi.nlm.nih.gov
Various living organisms have proven to influence human health significantly, either in a
commensal or pathogenic manner. Harnessing the creatures may remarkably improve …
commensal or pathogenic manner. Harnessing the creatures may remarkably improve …
Structural and molecular insights of protein tyrosine phosphatase 1B (PTP1B) and its inhibitors as anti-diabetic agents
Diabetes mellitus (DM), especially type 2 diabetes mellitus (T2DM), is the most disruptive
metabolic disorder globally affecting human health. To effectively manage this medical …
metabolic disorder globally affecting human health. To effectively manage this medical …
Significance of TRAIL/Apo-2 ligand and its death receptors in apoptosis and necroptosis signalling: Implications for cancer-targeted therapeutics
The human immune defense system routinely expresses the tumour necrosis factor (TNF)-
related apoptosis-inducing ligand (TRAIL), which is the most prevalent element for antitumor …
related apoptosis-inducing ligand (TRAIL), which is the most prevalent element for antitumor …
Bibliometric and Visualization Analysis of Stem Cell Therapy for Erectile Dysfunction
T Sun, Y Liu, P Yuan, Z Jia, J Yang - Drug Design, Development …, 2024 - Taylor & Francis
Purpose As a common male disease, erectile dysfunction (ED) seriously affects the physical
and mental health of patients. In recent years, studies have continued to point out the great …
and mental health of patients. In recent years, studies have continued to point out the great …
Application of aptamers in regenerative medicine
Z Luo, S Chen, J Zhou, C Wang, K Li, J Liu… - … in Bioengineering and …, 2022 - frontiersin.org
Regenerative medicine is a discipline that studies how to use biological and engineering
principles and operation methods to repair and regenerate damaged tissues and organs …
principles and operation methods to repair and regenerate damaged tissues and organs …
Endogenous bone marrow-derived stem cell mobilization and homing for in situ tissue regeneration
Y Chen, Y Li, F Lu, Z Dong - Stem Cells, 2023 - academic.oup.com
In mammals, post-injury repair and regenerative events rely predominantly on stem cell
function. Stem cell transplantation has achieved considerable success in animals but …
function. Stem cell transplantation has achieved considerable success in animals but …
Synthetic GPR40/FFAR1 agonists: An exhaustive survey on the most recent chemical classes and their structure-activity relationships
Free fatty acid receptor 1 (FFAR1 or GPR40) is a potential target for treating type 2 diabetes
mellitus (T2DM) and related disorders that have been extensively researched for many …
mellitus (T2DM) and related disorders that have been extensively researched for many …
From stem cells to pancreatic β-cells: strategies, applications, and potential treatments for diabetes
X Feng, H Zhang, S Yang, D Cui, Y Wu, X Qi… - Molecular and Cellular …, 2024 - Springer
Loss and functional failure of pancreatic β-cells results in disruption of glucose homeostasis
and progression of diabetes. Although whole pancreas or pancreatic islet transplantation …
and progression of diabetes. Although whole pancreas or pancreatic islet transplantation …
Synthesis and antiproliferative potency of 1, 3, 4-thiadiazole and 1, 3-thiazolidine-4-one based new binary heterocyclic molecules: in vitro cell-based anticancer …
Herein, we report the synthesis and anticancer properties of 21 new 1, 3, 4-thiadiazole-2-yl-
imino-thiazolidine-4-one containing binary heterocyclic molecules. Cytotoxicity of the …
imino-thiazolidine-4-one containing binary heterocyclic molecules. Cytotoxicity of the …