Cryptococcus neoformans and Cryptococcus gattii species complexes cause
meningoencephalitis with high fatality rates and considerable morbidity, particularly in …

Patients with suppressed immunity are at the highest risk for hospital-acquired infections.
Among these, invasive candidiasis is the most prevalent systemic fungal nosocomial …

MATERIALS AND METHODS Strains and media. C. neoformans var. grubii strains H99 (70),
KN99a (55), KN99 (55), KN99aNAT, and KN99NAT were maintained at 80 C. Cultures were …

The nature of microglia fascinated many prominent researchers in the 19th and early 20th
centuries, and in a classic treatise in 1932, Pio del Rio-Hortega formulated a number of …

The capsule of the fungal pathogen Cryptococcus neoformans has been studied extensively
in recent decades and a large body of information is now available to the scientific …

Cryptococcus neoformans (C. neoformans) is a pathogenic fungus with a global distribution.
Humans become infected by inhaling the fungus from the environment, and the fungus …

Cryptococcus neoformans (Cn) is an encapsulated yeast that is a facultative intracellular
pathogen and a frequent cause of human disease. The interaction of Cn with alveolar …

To produce chronic infection, microbial pathogens must escape host immune defenses.
Infection with the human pathogenic fungus Cryptococcus neoformans is typically chronic …

Phagocytic cells, such as neutrophils and macrophages, perform a critical role in protecting
organisms from infection by engulfing and destroying invading microbes [1]. Although some …

Microglia are endogenous brain macrophages that show distinct phenotypes such as
expression of myeloid antigens, ramified morphology, and presence within the neural …