Factors Influencing Mortality in Children with Central Nervous System Tumors: A Cohort Study on Clinical Characteristics and Genetic Markers

LM Torres-Espíndola, JC Pérez-De Marcos… - Genes, 2024 - mdpi.com
Multidrug resistance (MDR) commonly leads to cancer treatment failure because cancer
cells often expel chemotherapeutic drugs using ATP-binding cassette (ABC) transporters …

Prognostic role of TNF alpha, LT alpha, MDR1 and codon 72 Tp53 gene polymorphisms on multiple myeloma Egyptian patients

HM Hegazi, MS Elghonemy, MA El-Baiomy… - Leukemia Research, 2022 - Elsevier
Multiple Myeloma (MM) is a type of hematologic malignancies that characterized by
uncontrolled plasma cell proliferation. So, the diagnosis depends on the increased numbers …

Revisiting the effects of MDR1 Variants using computational approaches

T Gutman, T Tuller - RECOMB International Workshop on Comparative …, 2024 - Springer
P-glycoprotein, encoded by the MDR1 gene, is an ATP-dependent pump that exports
various substances out of cells. Its overexpression is related to multi drug resistance in many …