Mechanisms and Drug Intervention for Doxorubicin‐Induced Cardiotoxicity Based on Mitochondrial Bioenergetics

G Ling, X Wang, N Tan, J Cao, W Li… - Oxidative Medicine …, 2022 - Wiley Online Library
Doxorubicin (DOX) is an anthracycline chemotherapy drug, which is indispensable in
antitumor therapy. However, its subsequent induction of cardiovascular disease (CVD) has …

[HTML][HTML] Androgen-regulated cardiac metabolism in aging men

G Barrientos, P Llanos, C Basualto-Alarcón… - Frontiers in …, 2020 - frontiersin.org
The prevalence of cardiovascular mortality is higher in men than in age-matched
premenopausal women. Gender differences are linked to circulating sex-related steroid …

[HTML][HTML] Putting the personalized metabolic avatar into production: A comparison between deep-learning and statistical models for weight prediction

A Abeltino, G Bianchetti, C Serantoni, A Riente… - Nutrients, 2023 - mdpi.com
Nutrition is a cross-cutting sector in medicine, with a huge impact on health, from
cardiovascular disease to cancer. Employment of digital medicine in nutrition relies on …

Cardiac energy metabolism disorder mediated by energy substrate imbalance and mitochondrial damage upon tebuconazole exposure

T Ku, J Hu, M Zhou, Y Xie, Y Liu, X Tan, L Guo… - Journal of …, 2024 - Elsevier
Tebuconazole exposure has been described as an increasing hazard to human health. An
increasing number of recent studies have shown a positive association between …

[HTML][HTML] Stearoyl-CoA desaturase regulates angiogenesis and energy metabolism in ischemic cardiomyocytes

AM Gan, Z Tracz-Gaszewska… - International Journal of …, 2022 - mdpi.com
New blood vessel formation is a key component of the cardiac repair process after
myocardial infarction (MI). Hypoxia following MI is a major driver of angiogenesis in the …

[HTML][HTML] Astragaloside IV alleviates infarction induced cardiomyocyte injury by improving mitochondrial morphology and function

W Zhang, L Zhang, H Zhou, C Li, C Shao… - Frontiers in …, 2022 - frontiersin.org
The protective effect of astragaloside IV (AS-IV) on myocardial injury after myocardial
infarction has been reported. However, the underlying mechanism is still largely unknown …

[HTML][HTML] Metabolic reprogramming, gut dysbiosis, and nutrition intervention in canine heart disease

Q Li - Frontiers in Veterinary Science, 2022 - frontiersin.org
This review provides a state-of-the-art overview on recent advances in systems biology in
canine cardiac disease, with a focus on our current understanding of bioenergetics and …

[HTML][HTML] Intermittent cold stimulation affects energy metabolism and improves stress resistance in broiler heart

T Li, H Wei, S Zhang, X Liu, L Xing, Y Liu, R Gong, J Li - Poultry Science, 2024 - Elsevier
To investigate the effect of intermittent cold stimulation on cardiac energy metabolism and
cold resistance of broilers, 288 broilers were divided into 3 groups: control group (CC) and 2 …

Hypoxia-inducible factor-1: Regulatory mechanisms and drug therapy in myocardial infarction

J Pan, L Zhang, D Li, Y Li, M Lu, Y Hu, B Sun… - European Journal of …, 2023 - Elsevier
Myocardial infarction (MI), an acute cardiovascular disease characterized by coronary artery
blockage, inadequate blood supply, and subsequent ischemic necrosis of the myocardium …

[HTML][HTML] Heart failure symptom burden, dietary intake, and inflammation: An integrative review of the literature

E Davis, S Dunbar, M Higgins, W Kathryn… - Journal of integrative …, 2023 - journals.lww.com
Heart failure (HF) is characterized by high symptom burden including, but not limited to
fatigue, dyspnea, and edema. Up to 21.5% of HF patients experience significant depressive …