The cornea is a specialized, transparent, avascular, immune-privileged, and heavily
innervated tissue that affords 2/3rd of refraction to the eye. Ocular injuries, infections, and …

Eye drops are the most accessible therapy for ocular diseases, while inevitably suffering
from their lower bioavailability which highly restricts the treatment efficacy. The introduction …

Abstract Phosphatidylinositol 3 kinase (PI3K)/AKT (also called protein kinase B, PKB)
signalling regulates various cellular processes, such as apoptosis, cell proliferation, the cell …

Improper healing of the cornea after injury, infections or surgery can lead to corneal scar
formation, which is associated with the transition of resident corneal keratocytes into …

Corneal epithelial defects and excessive wound healing might lead to severe complications.
As stem cells can self-renew infinitely, they are a promising solution for regenerating the …

Wound refers to the place where human body is injured and ruptured. So, wounds in a
broad sense include not only skin wounds, but also damages of muscle, corneal, heart, and …

Tissue injury, one of the most common traumatic injuries in daily life, easily leads to
secondary wound infections. To promote wound healing and reduce scarring, various kinds …

Bacterial infections of the cornea, or bacterial keratitis (BK), are notorious for causing rapidly
fulminant disease and permanent vision loss, even among treated patients. In the last sixty …

The cornea is the window through which we see the world. Corneal clarity is required for
vision, and blindness occurs when the cornea becomes opaque. The cornea is covered by …

The ocular surface, which forms the interface between the eye and the external environment,
includes the cornea, corneoscleral limbus, the conjunctiva and the accessory glands that …