Comprehensive analysis and validation of SNX7 as a novel biomarker for the diagnosis, prognosis, and prediction of chemotherapy and immunotherapy response in …

J Chen, G Gao, Y Zhang, P Dai, Y Huang - BMC cancer, 2023 - Springer
Background Studies have demonstrated that Sorting nexin 7 (SNX7) functions as an anti-
apoptotic protein in liver tissue and plays a crucial role in the survival of hepatocytes during …

Identification and validation of eight lysosomes-related genes signatures and correlation with immune cell infiltration in lung adenocarcinoma

D Song, L Zhao, G Zhao, Q Hao, J Wu, H Ren… - Cancer Cell …, 2023 - Springer
Lung cancer is the leading cause of cancer-related death. Lysosomes are key degradative
compartments that maintain protein homeostasis. In current study, we aimed to construct a …

[HTML][HTML] ETS1-mediated Regulation of SOAT1 Enhances the Malignant Phenotype of Oral Squamous Cell Carcinoma and Induces Tumor-associated Macrophages …

Y Liu, L Shen, Y Li, X Sun, L Liang, S Jiang… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Oral squamous cell carcinoma (OSCC) is an aggressive cancer that poses a substantial
threat to human life and quality of life globally. Lipid metabolism reprogramming significantly …

Identification of hub genes significantly linked to tuberous sclerosis related-epilepsy and lipid metabolism via bioinformatics analysis

W Weiliang, R Yinghao, H Weiliang, Z Xiaobin… - Frontiers in …, 2024 - frontiersin.org
Background Tuberous sclerosis complex (TSC) is one of the most common genetic causes
of epilepsy. Identifying differentially expressed lipid metabolism related genes (DELMRGs) …

[HTML][HTML] A novel signature incorporating lipid metabolism-and immune-related genes to predict the prognosis and immune landscape in hepatocellular carcinoma

T Yang, Y Luo, J Liu, F Liu, Z Ma, G Liu, H Li… - Frontiers in …, 2023 - frontiersin.org
Background Liver hepatocellular carcinoma (LIHC) is a highly malignant tumor with high
metastasis and recurrence rates. Due to the relation between lipid metabolism and the tumor …

Construction of a prognostic model for lung adenocarcinoma based on m6A/m5C/m1A genes

H Ding, Y Teng, P Gao, Q Zhang… - Human Molecular …, 2024 - academic.oup.com
Background Developing a prognostic model for lung adenocarcinoma (LUAD) that utilizes
m6A/m5C/m1A genes holds immense importance in providing precise prognosis predictions …

Investigation of the Proteasome 26S Subunit, ATPase Family Genes as Potential Prognostic Biomarkers and Therapeutic Targets for Hepatocellular Carcinoma

L Feng, N Zhang, L Luo, J Liu, Y Yao… - Cancer Management …, 2024 - Taylor & Francis
Background Several studies suggest that Proteasome 26S Subunit, ATPase (PSMC) family
genes are of great importance in tumor progression and spreading, but the study for …

[HTML][HTML] Novel application of the ferroptosis-related genes risk model associated with disulfidptosis in hepatocellular carcinoma prognosis and immune infiltration

J Wei, J Wang, X Chen, L Zhang, M Peng - PeerJ, 2024 - peerj.com
Hepatocellular carcinoma (HCC) stands as the prevailing manifestation of primary liver
cancer and continues to pose a formidable challenge to human well-being and longevity …

Construction of a prognostic model based on memory CD4+ T cell–associated genes for lung adenocarcinoma and its applications in immunotherapy

Y Li, X Ye, H Huang, R Cao, F Huang… - CPT: Pharmacometrics …, 2024 - Wiley Online Library
The association between memory CD4+ T cells and cancer prognosis is increasingly
recognized, but their impact on lung adenocarcinoma (LUAD) prognosis remains unclear. In …

A Risk Score Based on Immune-and Oxidative Stress-Related LncRNAs Predicts Prognosis in Lung Adenocarcinoma: Insights from in vitro Experiments and Large …

X Liu, F Zhao, X Wang, Z Ma, H Yan, X Lu… - Journal of …, 2024 - Taylor & Francis
Background Long non-coding RNAs (lncRNAs) were demonstrated to be key to cancer
progression and highly associated with the tumor immune microenvironment. Oxidative …