Biological activities and distribution of plant saponins

SG Sparg, ME Light, J Van Staden - Journal of ethnopharmacology, 2004 - Elsevier
Plant saponins are widely distributed amongst plants and have a wide range of biological
properties. The more recent investigations and findings into their biological activities were …

Absorption, disposition, and pharmacokinetics of saponins from Chinese medicinal herbs: what do we know and what do we need to know more?

K Yu, F Chen, C Li - Current drug metabolism, 2012 - ingentaconnect.com
Saponins are a group of amphiphilic glycosides containing one or more sugar chains linked
to a nonpolar triterpene or steroid aglycone skeleton, which are believed to be responsible …

Antiviral activity of seven iridoids, three saikosaponins and one phenylpropanoid glycoside extracted from Bupleurum rigidum and Scrophularia scorodonia

P Bermejo, MJ Abad, AM Díaz, L Fernández… - Planta …, 2002 - thieme-connect.com
As part of our screening of antiviral agents from medicinal plants, 11 compounds from plant
origin (Bupleurum rigidum and Scrophularia scorodonia), three saikosaponins, seven …

Traditional Chinese medicines in the treatment of hepatocellular cancers: a systematic review and meta-analysis

P Wu, JJ Dugoua, O Eyawo, EJ Mills - Journal of Experimental & Clinical …, 2009 - Springer
Background Liver cancer is a common malignancy with a high mortality rate. Given the poor
prognosis associated with this cancer, many patients seek additional therapies that may …

Developments in high‐speed countercurrent chromatography and its applications in the separation of terpenoids and saponins

H Song, J Lin, X Zhu, Q Chen - Journal of separation science, 2016 - Wiley Online Library
High‐speed countercurrent chromatography is a liquid–liquid separation chromatographic
technique, which has the unique feature of eliminating irreversible adsorption using liquid …

Two new steroidal saponins from the rhizomes of Dioscorea panthaica and their cytotoxic activity

M Dong, XZ Feng, LJ Wu, BX Wang, T Ikejima - Planta medica, 2001 - thieme-connect.com
Two new steroidal saponins, dioscoresides C (1) and D (2), along with a new natural
product, pregnadienolone 3-O-β-gracillimatriose (3), and two known compounds …

Putative Genes Involved in Saikosaponin Biosynthesis in Bupleurum Species

TY Lin, CY Chiou, SJ Chiou - International Journal of Molecular Sciences, 2013 - mdpi.com
Alternative medicinal agents, such as the herb Bupleurum, are increasingly used in modern
medicine to supplement synthetic drugs. First, we present a review of the currently known …

Haemolytic activities and adjuvant effect of Bupleurum chinense saponins on the immune responses to ovalbumin in mice

HX Sun - Vaccine, 2006 - Elsevier
In this study, the haemolytic activities of Bupleurum chinense saponins (BCS) and its
adjuvant potentials on the immune responses of ICR mice against ovalbumin (OVA) were …

Pharmacokinetics, tissue distribution and excretion of coumarin components from Psoralea corylifolia L. in rats

L Feng, L Wang, X Jiang - Archives of pharmacal research, 2010 - Springer
Coumarin components from Psoralea corylifolia L. are novel drugs in which psoralen and
isopsoralen are the active components. The pharmacokinetics, tissue distribution and …

Metabolism of saikosaponin a in rats: diverse oxidations on the aglycone moiety in liver and intestine in addition to hydrolysis of glycosidic bonds

G Liu, Y Tian, G Li, L Xu, R Song, Z Zhang - Drug Metabolism and …, 2013 - ASPET
The main objective of the present study was to completely characterize the metabolites of
the triterpenoid saikosaponin a (SSa) in rats. To this aim, we compared the metabolites in …