The transcription factor NF-κB is a tightly regulated positive mediator of T-and B-cell
development, proliferation, and survival. The controlled activity of NF-κB is required for the …

Human T-cell lymphotropic virus type 1 (HTLV-1) has been identified as the causative agent
of adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic …

Human T-cell leukemia virus type 1 (HTLV-1) basic leucine zipper factor (HBZ) is
dispensable for HTLV-1–mediated cellular transformation in cell culture, but is required for …

The human T-cell leukemia virus type 1 (HTLV-1) transcriptional trans-activator Tax has
been demonstrated to have transforming activity in multiple cell culture and transgenic …

Natural antisense viral transcripts have been recognized in retroviruses, including human T-
cell leukemia virus type 1 (HTLV-1), HIV-1, and feline immunodeficiency virus (FIV), and …

Abstract HTLV-1 and HTLV-2 are highly related complex retroviruses that have been studied
intensely for nearly three decades because of their association with neoplasia …

Human T lymphotropic viruses (HTLVs) are complex deltaretroviruses that do not contain a
proto-oncogene in their genome, yet are capable of transforming primary T lymphocytes …

Studies on the molecular mechanisms of transformation of retrovirus-induced neoplasms in
domestic and laboratory animal species have provided insights into the genetic basis of …

Biochemical coupling of transcription factor NF-κB to antigen and co-stimulatory receptors is
required for the temporal control of T-cell proliferation. In contrast to its transitory activation …

Human T-cell leukemia virus type I (HTLV-I) 1 causes adult T-cell leukemia (ATL)(1–3). The
virus is also associated with a neuropathy/myelopathy termed HTLV-associated myelopathy …