Targeting molecular mechanisms underlying treatment efficacy and resistance in osteosarcoma: a review of current and future strategies

I Lilienthal, N Herold - International journal of molecular sciences, 2020 - mdpi.com
Osteosarcoma is the most common primary malignant bone tumour in children and
adolescents. Due to micrometastatic spread, radical surgery alone rarely results in cure …

Distinctions in bone matrix nanostructure, composition, and formation between osteoblast-like cells, MG-63, and human mesenchymal stem cells, UE7T-13

K Chatree, P Sriboonaied, C Phetkong, W Wattananit… - Heliyon, 2023 - cell.com
Osteoblast-like cells and human mesenchymal stem cells (hMSCs) are frequently employed
as osteoprogenitor cell models for evaluating novel biomaterials in bone healing and tissue …

[HTML][HTML] Ebastine exerts antitumor activity and induces autophagy by activating AMPK/ULK1 signaling in an IPMK-dependent manner in osteosarcoma

Z Pan, S Li, H Guo, Z Li, X Fei, S Chang… - … journal of biological …, 2023 - ncbi.nlm.nih.gov
Numerous studies have confirmed that in addition to interfering with the tumor inflammatory
environment, anti-inflammatory agents can directly increase apoptosis and sensitivity to …

RETRACTED ARTICLE: Parecoxib inhibits esophageal squamous cell carcinoma progression via the PDK1–AKT pathway

HM Huang, XY Huang, SP Wu, CK Chen… - Cellular & molecular …, 2022 - Springer
Background Parecoxib plays an important role in inhibition of human cancer. However, the
effect of parecoxib on esophageal squamous cell carcinoma (ESCC) is still not well known …

Design, synthesis, and biological evaluation of N-(4-substituted)-3-phenylisoxazolo [5, 4–d] pyrimidin-4-amine derivatives as apoptosis-inducing cytotoxic agents

NB Gaikwad, S Bansod, A Mara, R Garise… - Bioorganic & Medicinal …, 2021 - Elsevier
A library of new 3-phenylisoxazolo [5, 4–d] pyrimidines (8–10) was designed based on a
scaffold hybridization technique incorporating the important pharmacophoric features of 4 …

The Relationship between PBLS and Osteosarcoma Distribution in Different Subgroups and the Survival and Prognosis of Osteosarcoma

P Luo, P Zhou - Journal of Oncology, 2023 - Wiley Online Library
Objective. To analyze the differences in the distribution of lymphocytes (PBLS) in different
subgroups of osteosarcoma (OS) and the predictive value of related parameters on the …

Parecoxib inhibits tumorigenesis and angiogenesis in hepatocellular carcinoma through ERK–VEGF/MMPs signaling pathway

L Tian, YQ Huang, Y Liu, JW Liu, Y Liu - IUBMB life - Wiley Online Library
Parecoxib, a well‐recognized nonsteroidal anti‐inflammatory drug, has been reported to
possess anticancer properties in various tumor types. In this work, we aimed to investigate …

MRI apparent diffusion coefficient as potential biomarkers in the diagnosis of osteosarcoma

Q Zhuliang, X Lifeng, G Zhiqin, W Guowei, Z Ming - 2023 - researchsquare.com
Objective: To assess MRI apparent diffusion coefficient as potential biomarkers in the
diagnosis of osteosarcoma. Methods: 94 patients with osteosarcoma confirmed by surgical …

[引用][C] 帕瑞昔布钠对宫颈癌细胞COX-2/PGE2 通路及细胞学行为的影响

容凤娇, 杜佳楠, 蒋良富, 徐夏 - 中国免疫学杂志, 2022