The calcium–iron connection in ferroptosis-mediated neuronal death
S Gleitze, A Paula-Lima, MT Núñez… - Free Radical Biology and …, 2021 - Elsevier
Iron, through its participation in oxidation/reduction processes, is essential for the
physiological function of biological systems. In the brain, iron is involved in the development …
physiological function of biological systems. In the brain, iron is involved in the development …
[HTML][HTML] Balance of activity during a critical period tunes a developing network
I Hunter, B Coulson, T Pettini, JJ Davies, J Parkin… - Elife, 2024 - elifesciences.org
Developing neural circuits are influenced by activity and are especially sensitive to changes
in activity during critical periods (CPs) of development. Changes occurring during a CP often …
in activity during critical periods (CPs) of development. Changes occurring during a CP often …
[HTML][HTML] Menopause-Associated Depression: Impact of Oxidative Stress and Neuroinflammation on the Central Nervous System—A Review
G Liang, ASF Kow, R Yusof, CL Tham, YC Ho, MT Lee - Biomedicines, 2024 - mdpi.com
Perimenopausal depression, occurring shortly before or after menopause, is characterized
by symptoms such as emotional depression, anxiety, and stress, often accompanied by …
by symptoms such as emotional depression, anxiety, and stress, often accompanied by …
[HTML][HTML] Ryanodine receptor mediated calcium release contributes to ferroptosis induced in primary hippocampal neurons by GPX4 inhibition
S Gleitze, OA Ramírez, I Vega-Vásquez, J Yan… - Antioxidants, 2023 - mdpi.com
Ferroptosis, a newly described form of regulated cell death, is characterized by the iron-
dependent accumulation of lipid peroxides, glutathione depletion, mitochondrial alterations …
dependent accumulation of lipid peroxides, glutathione depletion, mitochondrial alterations …
[HTML][HTML] Eveningness chronotype and depressive affective temperament associated with higher high-sensitivity C-reactive protein in unipolar and bipolar depression
L Orsolini, L Ricci, S Pompili, A Cicolini… - Journal of affective …, 2023 - Elsevier
Background Several studies investigated the role of inflammation in the etiopathogenesis of
mood disorders. The aim of our cross-sectional study is evaluating baseline high-sensitivity …
mood disorders. The aim of our cross-sectional study is evaluating baseline high-sensitivity …
The effects of the superoxide dismutase mimetic, MnTMPyP, post hypoxia and oxygen glucose deprivation in isolated rat hippocampal slices
N Moreton, M Puzio, JJ O'Connor - Brain Research Bulletin, 2022 - Elsevier
The contributions of hypoxia, oxygen glucose deprivation (OGD) and oxidative stress, to the
pathophysiology of acute ischemic stroke (AIS) are well established and can lead to …
pathophysiology of acute ischemic stroke (AIS) are well established and can lead to …
[HTML][HTML] Ionizing radiation alters functional neurotransmission in Drosophila larvae
Y Zhang, Y Zhang, C Shen, S Hao, W Duan… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction Patients undergoing cranial ionizing radiation therapy for brain malignancies
are at increased risk of long-term neurocognitive decline, which is poorly understood and …
are at increased risk of long-term neurocognitive decline, which is poorly understood and …
APOE4 and sedentary lifestyle synergistically impair neurovascular function in the visual cortex of awake mice
Reduced cerebral blood flow occurs early in the development of Alzheimer's disease (AD),
suggesting an impairment in how the brain maintains its energy supply may contribute to …
suggesting an impairment in how the brain maintains its energy supply may contribute to …
Iron-Calcium Crosstalk in Neurodegenerative Diseases
M Kadian, G Sharma, A Kumar - Brain-Iron Cross Talk, 2022 - Springer
Iron and calcium have one thing in common: they are both required for appropriate neural
activity. Neuronal calcium impulses drive neurochemical release, proliferation of axon and …
activity. Neuronal calcium impulses drive neurochemical release, proliferation of axon and …
Ndr2 deficiency prevents spatial memory decline and proteostasis alterations in the ageing hippocampus
M Angel - 2023 - repo.bibliothek.uni-halle.de
The serine-threonine kinase Ndr2 regulates dendritic arborization and integrin signalling.
Among other cellular processes, it has also been strongly implicated in the regulation of …
Among other cellular processes, it has also been strongly implicated in the regulation of …