[HTML][HTML] Recent therapeutics in hepatocellular carcinoma
Z Fan, P Zhou, B Jin, G Li, L Feng… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is a malignant tumor of hepatocytes. It is a common
malignant tumor of the digestive system that often has initially hidden presentation followed …
malignant tumor of the digestive system that often has initially hidden presentation followed …
[HTML][HTML] The integration of machine learning and multi-omics analysis provides a powerful approach to screen aging-related genes and predict prognosis and …
J Shen, H Gao, B Li, Y Huang, Y Shi - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Background: Hepatocellular carcinoma (HCC) is a highly malignant tumor with high
incidence and mortality rates. Aging-related genes are closely related to the occurrence and …
incidence and mortality rates. Aging-related genes are closely related to the occurrence and …
Chemically engineered mTOR-nanoparticle blockers enhance antitumour efficacy
H Tang, D Dilimulati, Z Yang, K Zhou, X Chen, R Sun… - Ebiomedicine, 2024 - thelancet.com
Background Hepatocellular carcinoma (HCC) is a highly prevalent and deadly type of
cancer, and although pharmacotherapy remains the cornerstone of treatment, therapeutic …
cancer, and although pharmacotherapy remains the cornerstone of treatment, therapeutic …
Anti-cancer activity of sustained release capsaicin formulations
JC Merritt, SD Richbart, EG Moles, AJ Cox… - Pharmacology & …, 2022 - Elsevier
Abstract Capsaicin (trans-8-methyl-N-vanillyl-6-noneamide) is a hydrophobic, lipophilic
vanilloid phytochemical abundantly found in chili peppers and pepper extracts. Several …
vanilloid phytochemical abundantly found in chili peppers and pepper extracts. Several …
Emerging treatment modalities for systemic therapy in hepatocellular carcinoma
X Qing, W Xu, J Zong, X Du, H Peng, Y Zhang - Biomarker Research, 2021 - Springer
Hepatocellular carcinoma (HCC) has long been a major global clinical problem as one of
the most common malignant tumours with a high rate of recurrence and mortality. Although …
the most common malignant tumours with a high rate of recurrence and mortality. Although …
CDK4/6 inhibitors improve the anti-tumor efficacy of lenvatinib in hepatocarcinoma cells
G Digiacomo, C Fumarola, S La Monica… - Frontiers in …, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is the most frequent primary liver cancer with a poor
prognosis and limited treatment options. Considering that alterations of the CDK4/6-cyclin D …
prognosis and limited treatment options. Considering that alterations of the CDK4/6-cyclin D …
Discovery of Novel 1,2,3,4-Tetrahydrobenzofuro[2,3-c]pyridine Histone Deacetylase Inhibitors for Efficient Treatment of Hepatocellular Carcinoma
Z Lai, H Ni, X Hu, S Cui - Journal of Medicinal Chemistry, 2023 - ACS Publications
The development of histone deacetylase (HDAC) inhibitors for treating hematologic
malignancies has been widely investigated, while their role in hepatocellular carcinoma …
malignancies has been widely investigated, while their role in hepatocellular carcinoma …
Characterization of cellular senescence patterns predicts the prognosis and therapeutic response of hepatocellular carcinoma
Y Tang, C Guo, C Chen, Y Zhang - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
Background: Hepatocellular carcinoma (HCC) is a prevalent malignancy with a high
mortality rate. Cellular senescence, an irreversible state of cell cycle arrest, plays a …
mortality rate. Cellular senescence, an irreversible state of cell cycle arrest, plays a …
EGFR mediates epithelial‑mesenchymal transition through the Akt/GSK-3β/Snail signaling pathway to promote liver cancer proliferation and migration
J Gao, Z Huo, X Song, Q Shao, W Ren… - Oncology …, 2023 - spandidos-publications.com
Epidermal growth factor receptor (EGFR) is expressed in various types of cancer and is
associated with the malignant biological behavior of cancer cells. In the present study, the …
associated with the malignant biological behavior of cancer cells. In the present study, the …
A nationwide study on the current treatment status and natural prognosis of hepatocellular carcinoma in elderly
JJ Yoo, J Lee, GH Choi, MW Lee, DA Park - Scientific Reports, 2023 - nature.com
The aim of this study was to identify the treatment status and natural prognosis of
hepatocellular carcinoma (HCC) patients aged 65 years or older in Korea. We analyzed …
hepatocellular carcinoma (HCC) patients aged 65 years or older in Korea. We analyzed …