[HTML][HTML] Plant-based natural products for the discovery and development of novel anthelmintics against nematodes

M Liu, SK Panda, W Luyten - Biomolecules, 2020 - mdpi.com
Intestinal parasitic nematodes infect approximately two billion people worldwide. In the
absence of vaccines for human intestinal nematodes, control of infections currently relies …

[HTML][HTML] An appraisal of natural products active against parasitic nematodes of animals

JF Garcia-Bustos, BE Sleebs, RB Gasser - Parasites & Vectors, 2019 - Springer
Here, the scientific and patent literature on the activities of purified natural compounds has
been reviewed, with the aim of assessing their suitability as anthelmintic drug discovery …

[HTML][HTML] Drug development for onchocerciasis-the past, the present and the future

S Tagboto, V Orish - Frontiers in Tropical Diseases, 2022 - frontiersin.org
Onchocerciasis affects predominantly rural communities in Africa, and with small foci in
South America and the Yemen. The disease is a major cause of blindness and other …

[HTML][HTML] Characterization of the anti-Staphylococcus aureus fraction from Penthorum chinense Pursh stems

B Ding, Q Ding, S Zhang, Z Jin, Z Wang, S Li… - BMC complementary and …, 2019 - Springer
Abstract Background Methicillin-resistant Staphylococcus aureus (MRSA) causes serious
infections in hospitals. Penthorum chinense Pursh (PCP), employed by the Miao ethnic …

Methods for extraction, isolation and sequencing of cyclotides and others cyclic peptides with anti-helminthic activities: An overview

ON Eteme, EN Zondegoumba, YS Tadayozzi… - Parasitology …, 2023 - Elsevier
The mortality rate caused by parasitic worms on their hosts is of great concern and studies
have been carried out to find molecules to reduce the prevalence, host-parasite interaction …

Effects of the suspension of mass drug administration during the COVID-19 pandemic on onchocerciasis prevalence in the Bandjoun and Massangam health districts …

CM Shintouo, RA Shey, BN Yengo, NE Yaah, RN Teh… - Acta Tropica, 2023 - Elsevier
Onchocerciasis is an infectious disease of public health and socio-economic importance in
most parts of Sub-Saharan Africa. The objective of this study was to evaluate the effects of …

[HTML][HTML] In vitro nematocidal potential of hydro-ethanolic and aqueous extracts of Calotropis procera (Aiton) WT Aiton, 1811 (Apocynaceae) and Faidherbia albida …

A Mamat, Y Lame, FYS Adeline, N Yvette… - Heliyon, 2023 - cell.com
Onchocerciasis caused by Onchocerca volvulus Leuckart, 1893 is the second-world
infection responsible for human blindness. Except Ivermectin which has as targets the …

In Vitro Filaricidal Properties of Aqueous Extracts of Combretum nigricans (Combretaceae) on Onchocerca ochengi (Onchocercidae)

BB Ignagali, BR Galani Tietcheu… - Journal of …, 2024 - Wiley Online Library
Aim. Onchocerciasis is an endemic parasitic disease in sub‐Saharan Africa that significantly
impacts animal and human health. In Northern Cameroon, medicinal plants from the …

The potential use of natural products as sources of bioactive compounds: Searching for new treatments for neglected tropical diseases

J Borgo, LC Laurella, RN Rodríguez… - Studies in Natural …, 2024 - Elsevier
Neglected tropical diseases (NTDs) are prevalent diseases in tropical areas that affect more
than one billion people worldwide. They are caused by a variety of pathogens, including …

Macrofilaricidal Activity, acute and biochemical effects of three lichen species found on Mount Cameroon

TR Kang, JN Dinga, AE Orock, E Monya… - Journal of …, 2022 - Wiley Online Library
Onchocerciasis is a parasitic infection affecting a relatively small population globally but has
very devastating pathological outcomes. Ivermectin and recently moxidectin are the only …