Despite the recent advances in drug research, finding a safe, effective, and easy to use
chemotherapy for human African trypanosomiasis (HAT) remains a challenging task. The …

While both human and animal trypanosomiasis continue to present as major human and
animal public health constraints globally, detailed analyses of trypanosome wildlife reservoir …

Abstract Background The history of African indigenous cattle and their adaptation to
environmental and human selection pressure is at the root of their remarkable diversity …

Parasites, including African trypanosomes, utilize several immune evasion strategies to
ensure their survival and completion of their life cycles within their hosts. The defense factors …

Due mainly to properties such as high affinity and antigen specificity, antibodies have
become important tools for biomedical research, diagnosis, and treatment of several human …

Increasing evidence indicates that the Trypanosoma brucei flagellum (synonymous with
cilium) plays important roles in host-parasite interactions. Several studies have identified …

Background Human African trypanosomiasis progresses from an early (hemolymphatic)
stage, through CNS invasion to the late (meningoencephalitic) stage. In experimental …

Sleeping sickness is a parasitic infection caused by two species of trypanosomes
(Trypanosoma brucei gambiense and rhodesiense), transmitted by the tsetse fly. The …

African trypanosomes are single-celled extracellular protozoan parasites transmitted by
tsetse fly vectors across sub-Saharan Africa, causing serious disease in both humans and …

Trypanosomatids cause many diseases in and on animals (including humans) and plants.
Altogether, about 37 million people are infected with Trypanosoma brucei (African sleeping …