Clinical trials based on mesenchymal stromal cells are exponentially increasing: where are we in recent years?

U Galderisi, G Peluso, G Di Bernardo - Stem cell reviews and reports, 2022 - Springer
Mesenchymal stromal cells (MSCs), present in the stromal component of several tissues,
include multipotent stem cells, progenitors, and differentiated cells. MSCs have quickly …

Insight in Hypoxia‐Mimetic Agents as Potential Tools for Mesenchymal Stem Cell Priming in Regenerative Medicine

A Nowak-Stępniowska, PN Osuchowska… - Stem Cells …, 2022 - Wiley Online Library
Hypoxia‐mimetic agents are new potential tools in MSC priming instead of hypoxia
incubators or chambers. Several pharmaceutical/chemical hypoxia‐mimetic agents can be …

Comparison of EV-free fraction, EVs, and total secretome of amniotic mesenchymal stromal cells for their immunomodulatory potential: A translational perspective

A Papait, E Ragni, A Cargnoni, E Vertua… - Frontiers in …, 2022 - frontiersin.org
Amniotic mesenchymal stromal cells (hAMSCs) have unique immunomodulatory properties
demonstrated in vitro and in vivo in various diseases in which the dysregulated immune …

Update review on five top clinical applications of human amniotic membrane in regenerative medicine

AR Nejad, AA Hamidieh, MA Amirkhani, MM Sisakht - Placenta, 2021 - Elsevier
Due to the increasing number of studies performed in the field of regenerative medicine
during the last two decades, more analytic studies are still needed to clarify the future …

Intravenously transplanted mesenchymal stromal cells: a new endocrine reservoir for cardioprotection

A Huang, Y Liu, X Qi, S Chen, H Huang… - Stem cell research & …, 2022 - Springer
Background Intravenous administration of mesenchymal stromal cells (MSCs) has an
acknowledged competence of cardiac repair, despite a lack of systematic description of the …

ARID1A in cancer: Friend or foe?

B Fontana, G Gallerani, I Salamon, I Pace… - Frontiers in …, 2023 - frontiersin.org
ARID1A belongs to a class of chromatin regulatory proteins that function by maintaining
accessibility at most promoters and enhancers, thereby regulating gene expression. The …

The multifaceted roles of MSCs in the tumor microenvironment: interactions with immune cells and exploitation for therapy

A Papait, FR Stefani, A Cargnoni, M Magatti… - Frontiers in Cell and …, 2020 - frontiersin.org
The tumor microenvironment (TME) plays a critical role in tumorigenesis and is composed of
different cellular components, including immune cells and mesenchymal stromal cells …

Modelling the human placental interface in vitro—a review

M Cherubini, S Erickson, K Haase - Micromachines, 2021 - mdpi.com
Acting as the primary link between mother and fetus, the placenta is involved in regulating
nutrient, oxygen, and waste exchange; thus, healthy placental development is crucial for a …

An overview of mesenchymal stem cell heterogeneity and concentration

E Maličev, K Jazbec - Pharmaceuticals, 2024 - mdpi.com
Mesenchymal stem cells (MSCs) are of great interest in cell therapies due to the
immunomodulatory and other effects they have after autologous or allogeneic …

Stem cells and COVID-19: are the human amniotic cells a new hope for therapies against the SARS-CoV-2 virus?

RN Riedel, A Pérez-Pérez, V Sánchez-Margalet… - Stem Cell Research & …, 2021 - Springer
A new coronavirus respiratory disease (COVID-19) caused by the SARS-CoV-2 virus,
surprised the entire world, producing social, economic, and health problems. The COVID-19 …