The skin, including the hypodermis, is the largest body organ and is in constant contact with
the environment. Neurogenic inflammation is the result of the activity of nerve endings and …

Hypertrophic scar (HS) is a typical pathological response during skin injury, which can lead
to pain, itching, and contracture in patients and even affect their physical and mental health …

Transient receptor potential (TRP) channels are a class of transmembrane proteins that can
sense a variety of physical/chemical stimuli, participate in the pathological processes of …

Hypertrophic scar (HS) is a chronic inflammatory skin disorder characterized by excessive
deposition of extracellular matrix, and the mechanisms underlying their formation remain …

Botulinum neurotoxins (BoNTs), produced by Clostridium botulinum, have been used for the
treatment of various central and peripheral neurological conditions. Recent studies have …

Botulinum neurotoxins (BoNTs), derived from Clostridium botulinum, have been employed to
treat a range of central and peripheral neurological disease. Some studies indicate that …

Diabetes is a global disease with huge impacts on patients due to its complications, among
which non-healing wounds and depression are common and challenging. The neurokinin 1 …

Background Patients with hypertrophic scarring tend to experience recurrence after
treatment, which often occurs in areas of the body with high skin tension. Aims To evaluate …

Purpose: To compare clinical efficacy of pure silica gel and chitosan quaternary ammonium
salt silica gel (SQASC) in treatment of hypertrophic scars. Methods: Eighty-four patients with …

Hypertrophic scar (HS) is a fibrous proliferative disorder that occurs in the dermis after skin
injury. Studies have confirmed that Botulinum toxin type A (BTA) is effective in scar …