Echinocandins–structure, mechanism of action and use in antifungal therapy

M Szymański, S Chmielewska… - Journal of enzyme …, 2022 - Taylor & Francis
With increasing number of immunocompromised patients as well as drug resistance in fungi,
the risk of fatal fungal infections in humans increases as well. The action of echinocandins is …

Echinocandins for the treatment of invasive aspergillosis: from laboratory to bedside

M Aruanno, E Glampedakis… - Antimicrobial agents and …, 2019 - Am Soc Microbiol
ABSTRACT Echinocandins (caspofungin, micafungin, anidulafungin), targeting β-1, 3-
glucan synthesis of the cell wall, represent one of the three currently available antifungal …

Invasive aspergillosis in solid‐organ transplant recipients: guidelines from the American Society of Transplantation Infectious Diseases Community of Practice

S Husain, JF Camargo - Clinical transplantation, 2019 - Wiley Online Library
These updated AST‐IDCOP guidelines provide information on epidemiology, diagnosis, and
management of Aspergillus after organ transplantation. Aspergillus is the most common …

[HTML][HTML] Previously unknown species of Aspergillus

M Gautier, AC Normand, S Ranque - Clinical Microbiology and Infection, 2016 - Elsevier
The use of multi-locus DNA sequence analysis has led to the description of previously
unknown 'cryptic'Aspergillus species, whereas classical morphology-based identification of …

Azole Resistance in Aspergillus: A Growing Public Health Menace

DW Denning, DS Perlin - Future microbiology, 2011 - Taylor & Francis
CPA occurs in the immunocompetent host. Morbidity is considerable, including both
systemic and respiratory symptoms and hemoptysis. Even when treated, CPA has a 20–33 …

Identification by molecular methods and matrix-assisted laser desorption ionization–time of flight mass spectrometry and antifungal susceptibility profiles of clinically …

A Masih, PK Singh, S Kathuria, K Agarwal… - Journal of clinical …, 2016 - Am Soc Microbiol
Aspergillus species cause a wide spectrum of clinical infections. Although Aspergillus
fumigatus and Aspergillus flavus remain the most commonly isolated species in …

Susceptibility testing of fungi to antifungal drugs

M Sanguinetti, B Posteraro - Journal of fungi, 2018 - mdpi.com
Susceptibility testing of fungi against antifungal drugs commonly used for therapy is a key
component of the care of patients with invasive fungal infections. Antifungal susceptibility …

Antifungal susceptibilities of Aspergillus fumigatus clinical isolates obtained in Nagasaki, Japan

M Tashiro, K Izumikawa, A Minematsu… - Antimicrobial agents …, 2012 - Am Soc Microbiol
We investigated the triazole, amphotericin B, and micafungin susceptibilities of 196 A.
fumigatus clinical isolates in Nagasaki, Japan. The percentages of non-wild-type (non-WT) …

A reappraisal of Aspergillus section Nidulantes with descriptions of two new sterigmatocystin-producing species

V Hubka, A Nováková, SW Peterson, JC Frisvad… - Plant Systematics and …, 2016 - Springer
Aspergillus section Nidulantes is a speciose group of microscopic fungi whose species are
important in indoor air quality, food spoilage, mycotoxin production and human …

Molecular identification and antifungal susceptibility of clinically relevant and cryptic species of Aspergillus sections Flavi and Nigri

S Nargesi, J Jafarzadeh… - Journal of Medical …, 2022 - microbiologyresearch.org
Introduction. Aspergillus sections Flavi and Nigri comprise clinically relevant and cryptic
species that differ significantly in drug susceptibility, meaning that effective treatment …