The steroid hydroxylase CYP3A4 is the most abundant P-450 enzyme in the human liver,
and CYP3A enzymes metabolize more than 50% of prescription drugs. The CYP3A4 gene is …

PURPOSE: Quality of life is of great concern to patients considering treatment options for
prostate cancer. In the absence of clinical trial data clearly demonstrating that a particular …

Abstract Each year the American Cancer Society publishes a summary of existing
recommendations for early cancer detection, including updates, and/or emerging issues that …

Purpose: Since the 1980s with the increased use of abdominal imaging, such as
computerized abdominal tomography, renal cancer has commonly been diagnosed as an …

Institutional review board approval and written informed consent were obtained. Patients
with newly diagnosed prostate cancer and patients suspected of having recurrent prostate …

Purpose: Positive surgical margins adversely affect biochemical recurrence-free survival
after radical retropubic prostatectomy (RRP) for prostate cancer. We retrospectively …

Study Type–Therapy (case series) Level of Evidence 4 OBJECTIVE To examine the long‐
term rates of biochemical recurrence (BCR)‐free survival, cancer‐specific mortality (CSM) …

The advent of prostate-specific antigen (PSA) testing in the early 1980s revolutionized the
diagnosis of prostate cancer. As a result of PSA testing, there has been a surge in the …

Purpose: To evaluate retrospectively the accuracy of endorectal magnetic resonance (MR)
imaging for the depiction of tumor, extracapsular extension (ECE), and seminal vesicle …

Purpose Men with high-risk features (extraprostatic extension or high Gleason grade) face a
high risk of prostate cancer recurrence after radical prostatectomy. Clinical trials of adjuvant …