Oxidative stress and male infertility: current knowledge of pathophysiology and role of antioxidant therapy in disease management

E Barati, H Nikzad, M Karimian - Cellular and Molecular Life Sciences, 2020 - Springer
Infertility is a global health problem involving about 15% of couples. Approximately half of
the infertility cases are related to male factors. The oxidative stress, which refers to an …

[PDF][PDF] Aluminium toxicosis: a review of toxic actions and effects

IO Igbokwe, E Igwenagu… - Interdisciplinary …, 2019 - intapi.sciendo.com
Aluminium (Al) is frequently accessible to animal and human populations to the extent that
intoxications may occur. Intake of Al is by inhalation of aerosols or particles, ingestion of …

[HTML][HTML] Male infertility: the effect of natural antioxidants and phytocompounds on seminal oxidative stress

M Adewoyin, M Ibrahim, R Roszaman, ML Md Isa… - Diseases, 2017 - mdpi.com
Defective sperm function has been identified as the most common cause of infertility. The
objective of this study was to review recent findings on the effects of various antioxidants on …

[PDF][PDF] A review of procyanidin: Updates on current bioactivities and potential health benefits

R Dasiman, NM Nor, Z Eshak… - … Res. Appl. Chem, 2022 - biointerfaceresearch.com
Procyanidin is an abundant polyphenol found in nature. It is composed of flavan-3-ol units,
including catechin and epicatechin. Procyanidin is a polyphenolic polymer found in …

Protective effects of Vitis vinifera (grapes) and one of its biologically active constituents, resveratrol, against natural and chemical toxicities: A comprehensive review

J Tabeshpour, S Mehri… - Phytotherapy …, 2018 - Wiley Online Library
Vitis vinifera (grape) is one of the “most‐produced fruit” in the world. Grape seeds are a
valuable source of phenolic compounds including resveratrol (RSV). Grape and one of its …

Grape seed proanthocyanidin extract alleviates arsenic-induced oxidative reproductive toxicity in male mice

SG Li, YS Ding, NIU Qiang, SZ Xu, LJ Pang… - Biomedical and …, 2015 - Elsevier
Objective To determine the ability of grape seed proanthocyanidin extract (GSPE) in
alleviating arsenic-induced reproductive toxicity. Methods Sixty male Kunming mice …

Aluminum reproductive toxicity: a summary and interpretation of scientific reports

RA Yokel - Critical Reviews in Toxicology, 2020 - Taylor & Francis
Publications addressing aluminum (Al)-induced reproductive toxicity were reviewed. Key
details were compiled in summary tables. Approximate systemic Al exposure, a measure of …

Mechanism and impact of heavy metal-aluminum (Al) toxicity on male reproduction: Therapeutic approaches with some phytochemicals

FEM Ali, KSA Badran, MA Baraka, HS Althagafy… - Life Sciences, 2024 - Elsevier
Heavy metals are ubiquitous environmental toxicants that have been known to have a
serious effect on human and animal health. Aluminum (Al) is a widely distributed metal in …

Pathophysiology of obesity-related infertility and its prevention and treatment by potential phytotherapeutics

VVS Uddandrao, P Brahma Naidu… - International Journal of …, 2024 - nature.com
Background Obesity is a complex multifactorial disease in which the accumulation of excess
body fat has adverse health effects, as it can increase the risk of several problems, including …

[HTML][HTML] Carvedilol induces the antiapoptotic proteins Nrf2 and Bcl2 and inhibits cellular apoptosis in aluminum-induced testicular toxicity in male Wistar rats

SA Ahmed, WI Mohammed - Biomedicine & Pharmacotherapy, 2021 - Elsevier
The present study was carried out to explore the protective effect of carvedilol (CARV) on
aluminum chloride-induced testicular damage in Westar rats. Forty adult male rats, aged 8 …