Bisphosphonates—much more than only drugs for bone diseases

A Kuźnik, A Październiok-Holewa, P Jewula… - European journal of …, 2020 - Elsevier
Abstract α, α-Bisphosphonates (BPs) are well established in the treatment of bone diseases
such as osteoporosis and Paget's disease. Their successful application originates from their …

[HTML][HTML] Drugs for the management of osteoporosis: a review

DK Khajuria, R Razdan, DR Mahapatra - Revista brasileira de …, 2011 - SciELO Brasil
A osteoporose caracteriza-se por reduzida massa óssea e deterioração microarquitetural do
tecido ósseo, o que aumenta a fragilidade óssea e, portanto, a suscetibilidade a fraturas. A …

Albiflorin promotes osteoblast differentiation and healing of rat femoral fractures through enhancing BMP-2/Smad and Wnt/β-Catenin signaling

JH Kim, M Kim, SY Hong, EY Kim, H Lee… - Frontiers in …, 2021 - frontiersin.org
Fracture healing is related to osteogenic differentiation and mineralization. Recently, due to
the unwanted side effects and clinical limitations of existing treatments, various natural …

Dietary phlorizin enhances osteoblastogenic bone formation through enhancing β-catenin activity via GSK-3β inhibition in a model of senile osteoporosis

LD Antika, EJ Lee, YH Kim, MK Kang, SH Park… - The Journal of …, 2017 - Elsevier
Osteoporosis is one of the most prevalent forms of age-related bone diseases. Increased
bone loss with advancing age has become a grave public health concern. This study …

[HTML][HTML] Calcitonin: A useful old friend

A Srinivasan, FK Wong, D Karponis - Journal of musculoskeletal & …, 2020 - ncbi.nlm.nih.gov
Calcitonin regulates blood calcium levels and possesses certain clinically useful anti-
fracture properties. Specifically, it reduces vertebral fractures in postmenopausal …

Association between osteoporosis treatment and severe periodontitis in postmenopausal women

JS Passos-Soares, MIP Vianna, IS Gomes-Filho… - Menopause, 2017 - journals.lww.com
Objective: To estimate the association between osteoporosis treatment and severe
periodontitis in postmenopausal women. Methods: This cross-sectional study comprised of …

Current and emerging osteoporosis pharmacotherapy for women: state of the art therapies for preventing bone loss

A Fontalis, E Kenanidis, RA Kotronias… - Expert Opinion on …, 2019 - Taylor & Francis
Introduction: Pharmacological options to address the imbalance between bone resorption
and accrual in osteoporosis include anti-resorptive and osteoanabolic agents. Unique …

Bisphosphonate combination therapy in the management of postchemotherapy avascular necrosis of the femoral head in adolescents and young adults: a …

S Agarwala, SD Banavali… - Journal of Global Oncology, 2018 - ascopubs.org
Purpose With improved survival after chemotherapy for acute lymphoblastic leukemia (ALL),
it is imperative to maintain good quality of life as part of the management of post-therapy …

A paradigm shift in osteonecrosis treatment with bisphosphonates: a 20-year study

S Agarwala, M Vijayvargiya - JBJS Open Access, 2021 - journals.lww.com
Background: Bisphosphonates are proven to be effective in obviating the need for surgical
intervention in osteonecrosis of the femoral head. However, the late onset of pain relief …

[HTML][HTML] Single dose therapy of zoledronic acid for the treatment of transient osteoporosis of hip

S Agarwala, M Vijayvargiya - Annals of Rehabilitation …, 2019 - synapse.koreamed.org
Objective To shorten the natural course of transient osteoporosis of hip (TOH), which is a self-
limiting idiopathic condition and requires 6–12 months for the resolution of symptoms …