Coronary artery calcification (CAC), a measure of subclinical atherosclerosis, predicts future
symptomatic coronary artery disease (CAD). Identifying genetic risk factors for CAC may …

At the dawn of the new decade, it is judicious to reflect on the boom of knowledge about
polygenic risk for essential hypertension supplied by the wealth of genome-wide association …

Background We recently reported a link between plasma levels of 2 of 84 cardiovascular
disease (CVD)–related proteins and the 3 major CVDs, myocardial infarction, ischemic …

Hypertension (HT) is a modifiable risk factor for life-threatening cardiovascular diseases
(CVDs) including coronary artery disease, heart failure, or stroke. Despite significant …

Background The aim is to study common etiological pathways for 3 major cardiovascular
diseases (CVD), as reflected in multiple proteins. Methods and Results Eighty‐four proteins …

Background In vitro and in vivo studies have shown that certain cytokines and hormones
may play a role in the development and progression of type 2 diabetes (T2D). However …

BACKGROUND: Hypertension, a complex condition, is primarily defined based on blood
pressure readings without involving its pathophysiological mechanisms. We aimed to …

BACKGROUND: This study focused on circulating plasma protein profiles to identify
mediators of hypertension-driven myocardial remodeling and heart failure. METHODS: A …

Objective: Blood pressure is a complex, polygenic trait, and the need to identify
prehypertensive risks and new gene targets for blood pressure control therapies or …

Insulin is not only a pancreatic hormone of fundamental importance for glucose and lipid
metabolism, but also for vasodilation and blood pressure regulation. In normal subjects …