Progress and emerging techniques for biomaterial-based derivation of mesenchymal stem cells (MSCs) from pluripotent stem cells (PSCs)

N Prakash, J Kim, J Jeon, S Kim, Y Arai… - Biomaterials …, 2023 - spj.science.org
The use of mesenchymal stem cells (MSCs) for clinical purposes has skyrocketed in the past
decade. Their multilineage differentiation potentials and immunomodulatory properties have …

Tissue engineering for the temporomandibular joint

TM Acri, K Shin, D Seol, NZ Laird, I Song… - Advanced …, 2019 - Wiley Online Library
Tissue engineering potentially offers new treatments for disorders of the temporomandibular
joint which frequently afflict patients. Damage or disease in this area adversely affects …

Human ESC-derived MSCs outperform bone marrow MSCs in the treatment of an EAE model of multiple sclerosis

X Wang, EA Kimbrel, K Ijichi, D Paul, AS Lazorchak… - Stem cell reports, 2014 - cell.com
Current therapies for multiple sclerosis (MS) are largely palliative, not curative.
Mesenchymal stem cells (MSCs) harbor regenerative and immunosuppressive functions …

Engineering bone tissue from human embryonic stem cells

D Marolt, IM Campos, S Bhumiratana… - Proceedings of the …, 2012 - National Acad Sciences
In extensive bone defects, tissue damage and hypoxia lead to cell death, resulting in slow
and incomplete healing. Human embryonic stem cells (hESC) can give rise to all specialized …

Current perspectives in stem cell research for knee cartilage repair

P Orth, A Rey-Rico, JK Venkatesan… - Stem cells and …, 2014 - Taylor & Francis
Protocols based on the delivery of stem cells are currently applied in patients, showing
encouraging results for the treatment of articular cartilage lesions (focal defects …

Functional comparison of human-induced pluripotent stem cell-derived mesenchymal cells and bone marrow-derived mesenchymal stromal cells from the same donor

S Diederichs, RS Tuan - Stem cells and development, 2014 - liebertpub.com
Mesenchymal stem cells (MSCs) have a high potential for therapeutic efficacy in treating
diverse musculoskeletal injuries and cardiovascular diseases, and for ameliorating the …

Therapeutic cell delivery and fate control in hydrogels and hydrogel hybrids

C Wang, RR Varshney, DA Wang - Advanced drug delivery reviews, 2010 - Elsevier
Hydrogels are synthetic or natural polymer networks that closely mimic native extracellular
matrices. As hydrogel-based vehicles are being increasingly employed in therapeutic cell …

Halloysite nanotubes coated 3D printed PLA pattern for guiding human mesenchymal stem cells (hMSCs) orientation

F Wu, J Zheng, Z Li, M Liu - Chemical Engineering Journal, 2019 - Elsevier
Abstract Three-dimensional (3D) printed polymer scaffolds can build engineered tissue
constructs with complex and hierarchical structures, mechanical and biological …

One-step derivation of mesenchymal stem cell (MSC)-like cells from human pluripotent stem cells on a fibrillar collagen coating

Y Liu, AJ Goldberg, JE Dennis, GA Gronowicz… - PloS one, 2012 - journals.plos.org
Controlled differentiation of human embryonic stem cells (hESCs) and induced pluripotent
stem cells (iPSCs) into cells that resemble adult mesenchymal stem cells (MSCs) is an …

Tissue‐engineered cartilage: The crossroads of biomaterials, cells and stimulating factors

N Bhardwaj, D Devi, BB Mandal - Macromolecular bioscience, 2015 - Wiley Online Library
Damage to cartilage represents one of the most challenging tasks of musculoskeletal
therapeutics due to its limited propensity for healing and regenerative capabilities. Lack of …