Cocell polymers can be the best implants for replacing bone defects in patients. The
pluripotent stem cells produced from the patient and the nanofibrous polymeric scaffold that …

The field of regenerative medicine and tissue engineering is an ever evolving field that holds
promise in treating numerous musculoskeletal diseases and injuries. An important impetus …

Induced pluripotent stem cells (iPSCs), reprogrammed from adult somatic cells using
defined transcription factors, are regarded as a promising cell source for tissue engineering …

After progressive improvement in embryonic stem (ES) cell field, several studies have been
conducted to explore the usage of ES cells in regenerative medicine. Unlimited self renewal …

The BIRC5 gene encodes the oncofetal protein SURVIVIN, as well as four additional splice
variants (ΔEx3, 2B, 3B and 2α). SURVIVIN, an inhibitor of apoptosis, is also a chromosomal …

Administration of mesenchymal stem cells (MSCs) that have a reliable potential for
chondrogenic differentiation is a promising approach currently employed to treat articular …

Articular cartilage has a very limited regeneration capacity. Therefore, injury or degeneration
of articular cartilage results in an inferior mechanical stability, load-bearing capacity, and …

Background: Mesenchymal stem cells (MSCs) are important candidates for MSC-based
cellular therapy. Current paradigm states that MSCs support local progenitor cells in …

Background aims Mesenchymal stromal cells (MSC) have been used in a wide variety of pre-
clinical experiments and in an increasing number of human clinical trials. Although many of …

Human embryonic stem cells (hESCs) are an exciting cell source as they offer an unlimited
supply of cells that can differentiate into all cell types for regenerative medicine applications …