Drug resistance maps to guide intermittent preventive treatment of malaria in African infants
Intermittent preventive treatment of infants (IPTi) with sulphadoxine pyrimethamine (SP) is
recommended as an additional malaria control intervention in high transmission areas of …
recommended as an additional malaria control intervention in high transmission areas of …
Failure to detect Plasmodium vivax in West and Central Africa by PCR species typing
Background Plasmodium vivax is estimated to affect 75 million people annually. It is
reportedly absent, however, from west and central Africa due to the high prevalence of the …
reportedly absent, however, from west and central Africa due to the high prevalence of the …
Emergence of a dhfr Mutation Conferring High-Level Drug Resistance in Plasmodium falciparum Populations from Southwest Uganda
C Lynch, R Pearce, H Pota, J Cox… - The Journal of …, 2008 - academic.oup.com
Abstract The S108N, C59R, and N51I mutations in the Plasmodium falciparum gene that
encodes dihydrofolate reductase, dhfr, confer resistance to pyrimethamine and are common …
encodes dihydrofolate reductase, dhfr, confer resistance to pyrimethamine and are common …
Polymorphisms in Plasmodium falciparum K13-Propeller in Angola and Mozambique after the Introduction of the ACTs
C Escobar, S Pateira, E Lobo, L Lobo, R Teodosio… - PloS one, 2015 - journals.plos.org
We report the presence of SNPs in Plasmodium falciparum K13-propeller gene in two
African countries, Angola and Mozambique, where malaria is a serious public health …
African countries, Angola and Mozambique, where malaria is a serious public health …
Molecular Evidence of Increased Resistance to Anti-Folate Drugs in Plasmodium falciparum in North-East India: A Signal for Potential Failure of Artemisinin Plus …
PK Mohapatra, DK Sarma, A Prakash, K Bora… - PloS one, 2014 - journals.plos.org
North-east India, being a corridor to South-east Asia, is believed to play an important role in
transmitting drug resistant Plasmodium falciparum malaria to India and South Asia. North …
transmitting drug resistant Plasmodium falciparum malaria to India and South Asia. North …
[HTML][HTML] Differential effect of regional drug pressure on dihydrofolate reductase and dihydropteroate synthetase mutations in southern Mozambique
The prevalence and frequency of the dihydrofolate reductase (dhfr) and dihydropteroate
synthetase (dhps) mutations associated with sulfadoxine–pyrimethamine (SP) resistance at …
synthetase (dhps) mutations associated with sulfadoxine–pyrimethamine (SP) resistance at …
[PDF][PDF] Intermittent preventive treatment of malaria during pregnancy in central Mozambique
PE Brentlinger, M Dgedge… - Bulletin of the World …, 2007 - SciELO Public Health
PROBLEM: New WHO strategies for control of malaria in pregnancy (MiP) recommend
intermittent preventive treatment (IPTp), bednet use and improved case management …
intermittent preventive treatment (IPTp), bednet use and improved case management …
Rapid increase of Plasmodium falciparum dhfr/dhps resistant haplotypes, after the adoption of sulphadoxine-pyrimethamine as first line treatment in 2002, in southern …
S Enosse, P Magnussen, F Abacassamo… - Malaria Journal, 2008 - Springer
Background In late 2002, the health authorities of Mozambique implemented sulphadoxine-
pyrimethamine (SP)/amodiaquine (AQ) as first-line treatment against uncomplicated …
pyrimethamine (SP)/amodiaquine (AQ) as first-line treatment against uncomplicated …
Molecular markers of antifolate resistance in Plasmodium falciparum isolates from Luanda, Angola
BE Gama, GAL Pereira-Carvalho, FJI Lutucuta Kosi… - Malaria Journal, 2011 - Springer
Background Plasmodium falciparum malaria remains a leading health problem in Africa and
its control is seriously challenged by drug resistance. Although resistance to the …
its control is seriously challenged by drug resistance. Although resistance to the …
Ethnic variability of HIF-1α polymorphisms
The hypoxia-inducible factor-1α (HIF-1α) is a transcription factor that plays a crucial role in
the cellular response to hypoxia. The C1772T (P582S) and G1790A (A588T) …
the cellular response to hypoxia. The C1772T (P582S) and G1790A (A588T) …