The influence of subcortical shortcuts on disordered sensory and cognitive processing
The very earliest stages of sensory processing have the potential to alter how we perceive
and respond to our environment. These initial processing circuits can incorporate subcortical …
and respond to our environment. These initial processing circuits can incorporate subcortical …
The superior colliculus: cell types, connectivity, and behavior
The superior colliculus (SC), one of the most well-characterized midbrain sensorimotor
structures where visual, auditory, and somatosensory information are integrated to initiate …
structures where visual, auditory, and somatosensory information are integrated to initiate …
Paraventricular nucleus CRH neurons encode stress controllability and regulate defensive behavior selection
N Daviu, T Füzesi, DG Rosenegger, NP Rasiah… - Nature …, 2020 - nature.com
In humans and rodents, the perception of control during stressful events has lasting
behavioral consequences. These consequences are apparent even in situations that are …
behavioral consequences. These consequences are apparent even in situations that are …
An afferent white matter pathway from the pulvinar to the amygdala facilitates fear recognition
Our ability to rapidly detect threats is thought to be subserved by a subcortical pathway that
quickly conveys visual information to the amygdala. This neural shortcut has been …
quickly conveys visual information to the amygdala. This neural shortcut has been …
Investigating the subcortical route to the amygdala across species and in disordered fear responses
J McFadyen - Journal of Experimental Neuroscience, 2019 - journals.sagepub.com
Over the past few decades, evidence has come to light that there is a rapid subcortical
shortcut that transmits visual information to the amygdala, effectively bypassing the visual …
shortcut that transmits visual information to the amygdala, effectively bypassing the visual …
The “primitive brain dysfunction” theory of autism: the superior colliculus role
R Jure - Frontiers in Integrative Neuroscience, 2022 - frontiersin.org
A better understanding of the pathogenesis of autism will help clarify our conception of the
complexity of normal brain development. The crucial deficit may lie in the postnatal changes …
complexity of normal brain development. The crucial deficit may lie in the postnatal changes …
Shared behavioural impairments in visual perception and place avoidance across different autism models are driven by periaqueductal grey hypoexcitability in Setd5 …
LE Burnett, P Koppensteiner, O Symonova… - PLoS …, 2024 - journals.plos.org
Despite the diverse genetic origins of autism spectrum disorders (ASDs), affected individuals
share strikingly similar and correlated behavioural traits that include perceptual and sensory …
share strikingly similar and correlated behavioural traits that include perceptual and sensory …
A Non-canonical Excitatory PV RGC–PV SC Visual Pathway for Mediating the Looming-evoked Innate Defensive Response
M Yuan, S Jin, G Tan, S Song, Y Liu, H Wang… - Neuroscience …, 2024 - Springer
Parvalbumin-positive retinal ganglion cells (PV+ RGCs) are an essential subset of RGCs
found in various species. However, their role in transmitting visual information remains …
found in various species. However, their role in transmitting visual information remains …
GABAergic Retinal Ganglion Cells Projecting to the Superior Colliculus Mediate the Looming-Evoked Flight Response
M Yuan, G Tan, D Cai, X Luo, K Shen, Q Deng… - Neuroscience …, 2024 - Springer
The looming stimulus-evoked flight response to approaching predators is a defensive
behavior in most animals. However, how looming stimuli are detected in the retina and …
behavior in most animals. However, how looming stimuli are detected in the retina and …
Subcortical circuit dysfunctions delay perceptual decision-making in autism models
Autism spectrum disorders (ASD) include a range of neurodevelopmental conditions
characterised by social and communication difficulties, often co-occurring with sensory …
characterised by social and communication difficulties, often co-occurring with sensory …