Molecular imaging and disease theranostics with renal-clearable optical agents

P Cheng, K Pu - Nature Reviews Materials, 2021 - nature.com
Optical imaging in disease diagnosis and treatment benefits from high spatiotemporal
resolution and the availability of numerous optical agents. However, many optical imaging …

[HTML][HTML] Small-molecule fluorescence-based probes for interrogating major organ diseases

HH Han, H Tian, Y Zang, AC Sedgwick, J Li… - Chemical Society …, 2021 - pubs.rsc.org
Chemical tools that allow the real-time monitoring of organ function and the visualisation of
organ-related processes at the cellular level are of great importance in biological research …

Activatable molecular probes for fluorescence-guided surgery, endoscopy and tissue biopsy

Y Zhang, G Zhang, Z Zeng, K Pu - Chemical Society Reviews, 2022 - pubs.rsc.org
The real-time, dynamic optical visualization of lesions and margins ensures not only
complete resection of the malignant tissues but also better preservation of the vital …

A dual‐locked activatable phototheranostic probe for biomarker‐regulated photodynamic and photothermal cancer therapy

X Wei, C Zhang, S He, J Huang… - Angewandte Chemie …, 2022 - Wiley Online Library
Activatable phototheranostics holds promise for precision cancer treatment owing to the
“turn‐on” signals and therapeutic effects. However, most activatable phototheranostic …

Targeted multicolor in vivo imaging over 1,000 nm enabled by nonamethine cyanines

VG Bandi, MP Luciano, M Saccomano, NL Patel… - Nature …, 2022 - nature.com
Recent progress has shown that using wavelengths between 1,000 and 2,000 nm, referred
to as the shortwave-infrared or near-infrared (NIR)-II range, can enable high-resolution in …

Recent progresses in small-molecule enzymatic fluorescent probes for cancer imaging

HW Liu, L Chen, C Xu, Z Li, H Zhang… - Chemical Society …, 2018 - pubs.rsc.org
Abnormal enzymatic activities are directly related to the development of cancers. Identifying
the location and expression levels of these enzymes in live cancer cells have considerable …

Recent progress in NIR-II fluorescence imaging-guided drug delivery for cancer theranostics

S Roy, N Bag, S Bardhan, I Hasan, B Guo - Advanced drug delivery reviews, 2023 - Elsevier
Fluorescence imaging in the second near-infrared window (NIR-II) has become a prevalent
choice owing to its appealing advantages like deep penetration depth, low …

Molecular fluorophores for deep-tissue bioimaging

S Wang, B Li, F Zhang - ACS central science, 2020 - ACS Publications
Fluorescence imaging has made tremendous inroads toward understanding the complexity
of biological systems, but in vivo deep-tissue imaging remains a great challenge due to the …

[HTML][HTML] Synthetic biology-instructed transdermal microneedle patch for traceable photodynamic therapy

G He, Y Li, MR Younis, LH Fu, T He, S Lei, J Lin… - Nature …, 2022 - nature.com
Aminolevulinic acid-based photodynamic therapy heavily depends on the biological
transformation efficiency of 5-aminolevulinic acid to protoporphyrin IX, while the lack of an …

Light in diagnosis, therapy and surgery

SH Yun, SJJ Kwok - Nature biomedical engineering, 2017 - nature.com
Light and optical techniques have made profound impacts on modern medicine, with
numerous lasers and optical devices currently being used in clinical practice to assess …