[HTML][HTML] A review of the common neurodegenerative disorders: current therapeutic approaches and the potential role of nanotherapeutics

RNL Lamptey, B Chaulagain, R Trivedi… - International journal of …, 2022 - mdpi.com
Neurodegenerative disorders are primarily characterized by neuron loss. The most common
neurodegenerative disorders include Alzheimer's and Parkinson's disease. Although there …

[HTML][HTML] Neural stem cell transplantation for neurodegenerative diseases

R De Gioia, F Biella, G Citterio, F Rizzo, E Abati… - International journal of …, 2020 - mdpi.com
Neurodegenerative diseases are disabling and fatal neurological disorders that currently
lack effective treatment. Neural stem cell (NSC) transplantation has been studied as a …

[HTML][HTML] Recent advances in molecular pathways and therapeutic implications targeting neuroinflammation for Alzheimer's disease

R Dhapola, SS Hota, P Sarma, A Bhattacharyya… - …, 2021 - Springer
Alzheimer's disease (AD) is a major contributor of dementia leading to the degeneration of
neurons in the brain with major symptoms like loss of memory and learning. Many evidences …

[HTML][HTML] Comprehensive research on past and future therapeutic strategies devoted to treatment of amyotrophic lateral sclerosis

B Sever, H Ciftci, H DeMirci, H Sever, F Ocak… - International journal of …, 2022 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a rapidly debilitating fatal neurodegenerative disorder,
causing muscle atrophy and weakness, which leads to paralysis and eventual death. ALS …

[HTML][HTML] SOD1 misplacing and mitochondrial dysfunction in amyotrophic lateral sclerosis pathogenesis

F Tafuri, D Ronchi, F Magri, GP Comi… - Frontiers in cellular …, 2015 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease presenting as sporadic
(sALS) or familial (fALS) forms. Even if the list of the genes underlining ALS greatly …

[HTML][HTML] The biogenesis of miRNAs and their role in the development of amyotrophic lateral sclerosis

J Liu, F Zhou, Y Guan, F Meng, Z Zhao, Q Su, W Bao… - Cells, 2022 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects upper and
lower motor neurons. As there is no effective treatment for ALS, it is particularly important to …

miRNAs: key players in neurodegenerative disorders and epilepsy

HK Karnati, MK Panigrahi, RK Gutti… - Journal of …, 2015 - content.iospress.com
MicroRNAs (miRNAs) are endogenous,∼ 22 nucleotide, non-coding RNA molecules that
function as post-transcriptional regulators of gene expression. miRNA dysregulation has …

Significance of optineurin mutations in glaucoma and other diseases

Y Minegishi, M Nakayama, D Iejima, K Kawase… - Progress in retinal and …, 2016 - Elsevier
Glaucoma is one of the leading causes of bilateral blindness, affecting nearly 57 million
people worldwide. Glaucoma is characterized by a progressive loss of retinal ganglion cells …

[HTML][HTML] Insights into the identification of a molecular signature for amyotrophic lateral sclerosis exploiting integrated microRNA profiling of iPSC-derived motor …

M Rizzuti, V Melzi, D Gagliardi, D Resnati… - Cellular and Molecular …, 2022 - Springer
Amyotrophic lateral sclerosis (ALS) is a rare neurodegenerative disorder characterized by
progressive degeneration of motor neurons (MNs). Most cases are sporadic, whereas 10 …

Ameliorating potential of curcumin and its analogue in central nervous system disorders and related conditions: a review of molecular pathways

P Joshi, A Bisht, S Joshi, D Semwal… - Phytotherapy …, 2022 - Wiley Online Library
Curcumin, isolated from turmeric (Curcuma longa L.) is one of the broadly studied
phytomolecule owing to its strong antioxidant and anti‐inflammatory potential and has been …