Self-organization in amoeboid motility

A Callan-Jones - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Amoeboid motility has come to refer to a spectrum of cell migration modes enabling a cell to
move in the absence of strong, specific adhesion. To do so, cells have evolved a range of …

Adaptive nonequilibrium design of actin-based metamaterials: Fundamental and practical limits of control

S Chennakesavalu, SK Manikandan… - Proceedings of the …, 2024 - National Acad Sciences
The adaptive and surprising emergent properties of biological materials self-assembled in
far-from-equilibrium environments serve as an inspiration for efforts to design nanomaterials …

Microscopic interactions control a structural transition in active mixtures of microtubules and molecular motors

B Najma, WS Wei, A Baskaran… - Proceedings of the …, 2024 - National Acad Sciences
Microtubules and molecular motors are essential components of the cellular cytoskeleton,
driving fundamental processes in vivo, including chromosome segregation and cargo …

Physics-informed graph neural networks enhance scalability of variational nonequilibrium optimal control

J Yan, GM Rotskoff - The Journal of Chemical Physics, 2022 - pubs.aip.org
When a physical system is driven away from equilibrium, the statistical distribution of its
dynamical trajectories informs many of its physical properties. Characterizing the nature of …

Theoretical limits of energy extraction in active fluids

S Shadkhoo, M Thomson - Physical Review Research, 2024 - APS
Active materials form a class of far-from-equilibrium systems that are driven internally and
exhibit self-organization, which can be harnessed to perform mechanical work. Inspired by …

Methods and conversations in (post) modern thermodynamics

F Avanzini, M Bilancioni, V Cavina… - SciPost Physics Lecture …, 2024 - scipost.org
Lecture notes after the doctoral school (Post) Modern Thermodynamics held at the
University of Luxembourg, December 2022, 5-7, covering and advancing continuous-time …

Biased ensembles of pulsating active matter

WD Piñeros, É Fodor - arXiv preprint arXiv:2403.16961, 2024 - arxiv.org
We discover unexpected connections between packing configurations and rare fluctuations
in dense systems of active particles subject to pulsation of size. Using large deviation theory …

Contractile to extensile transitions and mechanical adaptability enabled by activity in cytoskeletal structures

A Lamtyugina, DS Banerjee, Y Qiu, S Vaikuntanathan - bioRxiv, 2024 - biorxiv.org
In this study, we investigate the response of self-assembled cytoskeletal structures to
external mechanical perturbations, focusing on filament and crosslinker mixtures in two …

Short Trajectory Methods for Rare Event Analysis and Sampling

JC Strahan - 2024 - knowledge.uchicago.edu
A fundamental problem in computer simulation of systems of biophysical interest is the
separation of timescales. This refers to the fact that stable integration of the equations that …

Computational Simulation of Cytoskeleton Protein Filament Network Influenced by Motor Proteins and Crosslinking Protein

CM Gunter - 2023 - search.proquest.com
Stochastic computational models, which are based on mathematical approaches rooted in
probability analyses, are powerful tools that are well suited for the simulation of active matter …